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Prediction of microRNAs affecting the syncytin-1 (HERV-W) and syncytin-2 (HERV-FRD) genes regulation in endometriosis and miscarriage.

Abnormal expression levels of microRNAs are associated with numerous diseases in the female reproductive tract. A small subset of human endogenous retroviruses (HERVs) genes have retained open reading frames (ORFs) …

Published: Dec. 6, 2025, midnight
The "double-edged sword" effect of non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of endometriosis (EMS).

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to alleviate pain associated with endometriosis (EMS), yet the impact of their long-term use on disease progression remains unclear. This study investigates the …

Published: Dec. 6, 2025, midnight
Personalized Estimation of Fatigue in Endometriosis Using Wrist-Worn Actigraphy Data and Hierarchical Bayesian Modeling.

Endometriosis is a common chronic condition associated with debilitating pain and fatigue. Wearable technology has the potential to improve symptom monitoring in endometriosis where symptom severity has been traditionally evaluated …

Published: Dec. 5, 2025, midnight
Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review).

Endometriosis is a complex, chronic inflammatory gynecological disorder with estrogen‑dependent characteristics that severely impairs the quality of life of women and potentially leads to infertility. However, its pathogenesis remains poorly …

Published: Dec. 5, 2025, midnight
Impact of Intraoperative Clonidine on Postoperative Opioid Use in Patients With Endometriosis: A Randomized Controlled Trial.

Patients with endometriosis undergoing surgery are at risk of moderate-to-severe postoperative pain. Clonidine, an alpha-2 agonist with analgesic properties, may improve multimodal pain management in these patients.

Published: Dec. 4, 2025, midnight
Spinal-Cord Stimulation for Intractable, Visceral Pain Associated With Endometriosis: Positive Results of a Feasibility Study.

Endometriosis, an estrogen-dependent chronic inflammatory disease, can cause visceral pain. Owing to its chronic nature, treatment can be challenging and insufficient in reducing all symptoms despite adequate management. Spinal-cord stimulation …

Published: Dec. 3, 2025, midnight
AI-Driven Advances in Women's Health Diagnostics: Current Applications and Future Directions.

Background: Women's health has historically served as an incubator for major medical innovations yet often faces relative neglect in sustained funding and implementation. The rise of artificial intelligence (AI) and …

Published: Dec. 3, 2025, midnight
The pelvic pain bias assessment: a new assessment of interpretation bias specific to pelvic pain.

Pelvic pain is a common and often debilitating experience with limited treatment options. Improving understanding of the psychosocial mechanisms involved in pelvic pain experiences will enhance the efficacy of pain …

Published: Dec. 2, 2025, midnight
High inhibition ratio and transformation index of 2 mg dienogest: further evidence for its use in endometriosis treatment.

Endometriosis is a common, chronic disease with a high burden for women, characterised by the implantation of endometrial cells outside the uterus. Many different treatments have been proposed for this …

Published: Dec. 2, 2025, midnight
Natural bioactive compounds and herbal medicines targeting common signaling pathways in endometriosis: mechanisms and therapeutic implications.

For a very long time, herbal treatments have served as remedies for various humans and animals. Natural compounds typically have multiple pharmacological actions because they interact with various biological targets. …

Published: Dec. 2, 2025, midnight
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