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Evaluating serum cyclooxygenase-2 and vascular endothelial growth factor as biomarkers for endometriosis severity in reproductive-age women.

Endometriosis affects approximately 10-15% of reproductive-age women and up to 70% of those with chronic pelvic pain, with diagnosis typically relying on invasive laparoscopy with histopathological confirmation. Cyclooxygenase-2 (COX-2) and …

Published: Jan. 13, 2026, midnight
Experiences of women with endometriosis & their partners in India: Findings from a qualitative study.

Background & objectives Endometriosis, a chronic inflammatory condition, affects approximately 10 per cent of reproductive-age women in India. This study aimed to explore the experiences of women with endometriosis and …

Published: Jan. 12, 2026, midnight
Global RNA expression analysis of patient samples identified potential diagnostic biomarkers specific for peritoneal, ovarian and deep endometriosis.

Endometriosis is a chronic and debilitating gynecological disorder affecting approximately 10% of women of reproductive age worldwide (190 million), often leading to chronic pain, infertility, and considerable economic burden. Despite …

Published: Jan. 12, 2026, midnight
Development and validation of a nomogram model for predicting natural pregnancy after hysteroscopy and laparoscopy in patients with tubal infertility complicated with pelvic endometriosis.

This study aimed to construct and validate a nomogram for predicting natural pregnancy after hysteroscopy and laparoscopy in patients with tubal infertility and pelvic endometriosis, providing a basis for precise …

Published: Jan. 11, 2026, midnight
Bidirectional causal relationship between 91 blood cells and endometriosis at different sites: A Mendelian randomization study.

To explore the genetic associations between 91 types of blood cells (BCs) and endometriosis (EMs), providing references for the treatment of EMs. Forward Mendelian randomization (MR) analysis was conducted with …

Published: Jan. 11, 2026, midnight
Regarding "Efficacy of Dienogest Versus GnRH Agonists After Endometriosis Surgery: A Systematic Review and Meta-Analysis".

Published: Jan. 10, 2026, midnight
Significance of Follicle-Stimulating Hormone Receptor Gene Single-Nucleotide Polymorphism rs6165/rs6166 Analysis for Infertility-Associated Ovarian Disease Susceptibility Prediction and Optimized Individualized Ovulation Induction/Ovarian Stimulation.

Follicle-stimulating hormone receptor (FSHR) is expressed on the plasma membrane of granulosa cells in the ovarian follicles. FSHR is involved in the development and maturation of Graafian follicles, along with …

Published: Jan. 10, 2026, midnight
Regarding "Is endometriosis staging related to the type and intensity of patients' complaints? A systematic review and meta-analysis".

Firstly, this meta-analysis[1] included a total of eight studies, seven of which used the rASRM classification, while only one applied the ENZIAN classification; the latter was not included in the …

Published: Jan. 9, 2026, midnight
Transcriptomic landscape of coexisting ovarian clear cell carcinoma and endometriosis: Insights into malignant transformation.

This study investigateted the malignant transformation of endometriosis (EMS) into ovarian clear cell carcinoma (OCCC) using spatial transcriptomics and single-cell RNA sequencing (scRNA-seq) integration. Tissues with coexisting EMS and OCCC …

Published: Jan. 7, 2026, midnight
Comparative safety profiles of spironolactone, eplerenone, and finerenone: a pharmacovigilance study based on FAERS data from 2004 to 2024.

Spironolactone, eplerenone, and finerenone are three commonly used mineralocorticoid receptor antagonists (MRAs) with cardioprotective and renoprotective effects. However, comparative real-world safety evaluations remain limited. This study aimed to assess and …

Published: Jan. 7, 2026, midnight
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