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NHE7 drives endometrial cancer progression by delaying senescence through cAMP/CREB/GRIN2B axis-mediated Ca²⁺ influx - Nature

NHE7 drives endometrial cancer progression by delaying senescence through cAMP/CREB/GRIN2B axis-mediated Ca²⁺ influx Nature

Published: June 5, 2025, 9:33 p.m.
Extracellular matrix stiffness in endometrial cancer: driving progression and modulating treatment sensitivity via the ROCK1/YAP1 axis - Nature

Extracellular matrix stiffness in endometrial cancer: driving progression and modulating treatment sensitivity via the ROCK1/YAP1 axis Nature

Published: May 15, 2025, 12:37 a.m.
Current Insights into Endometriosis: Hormonal Management, Clinical Outcomes, and Opportunities for Progress.

Endometriosis, a prevalent women's health condition, is associated with persistent pelvic pain and infertility. Despite ongoing research, its precise disease mechanism remains elusive, impeding the discovery of a definitive cure. …

Published: April 8, 2025, midnight
Adoptive transfer of regulatory T cells inhibits the progression of endometriosis-like lesions in regulatory T-cell-depleted mice.

Does the restoration of regulatory T cells (Tregs) suppress the progression of endometriosis?

Published: April 3, 2025, midnight
Optimizing Management Strategies for Advanced Endometrial Cancer Progression After IO-Chemo - OncLive

Optimizing Management Strategies for Advanced Endometrial Cancer Progression After IO-Chemo OncLive

Published: March 31, 2025, 2:14 p.m.
SIRT7 facilitates endometrial cancer progression by regulating PTEN stability in an estrogen-dependent manner - Nature.com

SIRT7 facilitates endometrial cancer progression by regulating PTEN stability in an estrogen-dependent manner Nature.com

Published: March 27, 2025, 6:35 a.m.
Ferroptosis in Endometriosis: Traditional Chinese Medicine Interventions and Mechanistic Insights.

Endometriosis (EMS) is a chronic, estrogen-dependent inflammatory disease affecting 5-10% of women of reproductive age, characterized by the growth of endometrial tissue on the outside of the uterus. The dysregulation …

Published: March 27, 2025, midnight
Transcription factor addictions: exploring the potential Achilles' Heel of endometriosis.

A considerable number of women of reproductive age suffer from endometriosis worldwide. There is a significant physical, mental, and financial burden on patients affected by this condition in terms of …

Published: March 27, 2025, midnight
A novel senotherapeutic strategy with azithromycin for preventing endometriosis progression.

Endometriosis is an estrogen-dependent chronic inflammatory disease, however the mechanisms underlying inflammation remain unclear. Non-hormonal drugs that can prevent endometriosis progression and resolve endometriotic infertility are urgently required. We thus …

Published: March 26, 2025, midnight
A new perspective on endometriosis: Integrating eQTL mendelian randomization with transcriptomics and single-cell data analyses.

Endometriosis is caused by the migration of endometrial cells to locations outside the uterine lining. Despite the increasing prevalence of endometriosis, there has been limited research on genetic effects, and …

Published: March 26, 2025, midnight
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