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Correlation of Sonographic and Intraoperative Findings of Deep-Infiltrating Endometriosis.

Endometriosis is a chronic inflammatory condition affecting approximately 5%-10% of reproductive-aged women. Transvaginal ultrasound (TVUS) is increasingly used to diagnose deep-infiltrating endometriosis (DIE). This study assesses the sonographic accuracy of …

Published: Aug. 6, 2025, midnight
Regulatory Effects of Endometriosis-Associated Genetic Variants: A Multi-Tissue eQTL Analysis.

Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by the ectopic presence of endometrial-like tissue. Although genome-wide association studies (GWAS) have identified susceptibility variants, their tissue-specific regulatory impact remains poorly …

Published: Aug. 6, 2025, midnight
Identification of Candidate Genes for Endometriosis in a Three-Generation Family with Multiple Affected Members Using Whole-Exome Sequencing.

Background: Endometriosis is a chronic inflammatory condition affecting 10-15% of women of reproductive age. Genome-wide association studies (GWASs) have accounted for only a fraction of its high heritability, indicating the …

Published: Aug. 6, 2025, midnight
Epithelial characteristics of ovarian clear cell carcinoma at single-cell resolution.

Ovarian clear cell carcinoma (OCCC) represents a rare and aggressive subtype of epithelial ovarian cancer with distinctive clinical and molecular characteristics. However, the identification, origin, and molecular features of the …

Published: Aug. 5, 2025, midnight
Design of a peripherally biased NPSR1 antagonist for neuropeptide S induced inflammation.

Neuropeptide S (NPS) is a potent agonist for the GPCR receptor NPSR1, implicated in various physiological and pathological processes, including inflammation. NPSR1 gene polymorphisms have been linked to asthma, inflammatory …

Published: Aug. 5, 2025, midnight
Surgical Reconstruction of Abdominal Wall Endometriosis Post-Cesarean Section: A Monocentric Experience of a Rare Pathology.

Background: Abdominal wall endometriosis (AWE) is a rare pathological condition that mostly occurs in the post-cesarean section. This study aimed to describe the surgical approach employed in treating 31 patients …

Published: Aug. 1, 2025, midnight
Comorbidity analysis and clustering of endometriosis patients using electronic health records.

Endometriosis is a prevalent, complex, inflammatory condition associated with a diverse range of symptoms and comorbidities. Despite its substantial burden on patients, population-level studies that explore its comorbid patterns and …

Published: July 31, 2025, midnight
The association of infertility, miscarriage, stillbirth, and parity with osteoporosis: a pooled analysis of five cohort studies.

To test, among women with natural menopause, whether: infertility, miscarriage, stillbirth, and low parity are associated with a higher risk of osteoporosis; menopause age can partly explain their associations.

Published: July 30, 2025, midnight
Current Understanding of Endometriosis Pathophysiology and Future Perspectives.

Endometriosis-the growth of uterine-like tissue outside the uterus-is a devastating disease that severely reduces the quality of life of those affected, resulting in missed days from school and work due …

Published: July 30, 2025, midnight
The Gut-Endometriosis Axis: Genetic Mechanisms and Public Health Implications.

Background/Objectives: Endometriosis is a chronic, estrogen-driven gynecological disorder affecting approximately 10% of reproductive-aged women worldwide, with significant physical, psychosocial, and socioeconomic impacts. Recent research suggests a possible involvement of the …

Published: July 30, 2025, midnight
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