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Personalized Vaginal Drug Delivery through 3D Printing: Techniques, Challenges, and Future Perspectives.

Vaginal disorders in reproductive‑age women, including bacterial vaginosis (affecting 23-29%), endometriosis, etc., are increasing alarmingly day by day worldwide. Vaginal drug delivery (VDD) has garnered notable attention in the pharmaceutical …

Published: Nov. 26, 2025, midnight
Impact of dietary patterns on pain and quality of life in ovarian and deep endometriosis: observational study for nutritional interventions.

Endometriosis impairs multiple dimensions of women's lives. Ovarian endometrioma and deep endometriosis present distinct clinical profiles. The dietary pattern has shown controversial data both for pain control and in the …

Published: Nov. 26, 2025, midnight
Pregnancy in women with advanced endometriosis and adenomyosis: possible complications and the role of surgery.

Advanced endometriosis (stage III-IV, per the revised American Society for Reproductive Medicine (rARSM) classification of endometriosis) is associated with a range of pregnancy-related complications. Despite growing evidence, awareness of these …

Published: Nov. 26, 2025, midnight
Appendiceal endometriosis: an uncommon manifestation of deep infiltrating endometriosis.

Appendiceal endometriosis is a rare cause of acute appendicitis, accounting for approximately 1% of cases.This report describes a case of a female patient presenting with right iliac fossa pain and …

Published: Nov. 26, 2025, midnight
Network pharmacology prediction of UA in targeting endometriosis progression to endometrial cancer.

Endometriosis is a gynecological disorder predominantly affecting women of reproductive age and is considered a potential risk factor for the development of endometrial cancer. However, the molecular mechanisms underlying the …

Published: Nov. 26, 2025, midnight
The Great Masquerader: Accessory Cavitating Uterine Mass (ACUM). Evaluation, diagnosis, and surgical management.

Accessory cavitating uterine masses (ACUM) are rare, cystic uterine anomalies associated with an otherwise normal uterus and reproductive tract. They are diagnosed via a presence of a noncommunicating accessory cavity …

Published: Nov. 26, 2025, midnight
Urine and Serum miRNA Signatures for the Non-Invasive Diagnosis of Adenomyosis: A Machine Learning-Based Pilot Study.

Background: Adenomyosis remains difficult to diagnose non-invasively due to clinical overlap with endometriosis and the limited specificity of imaging techniques. This pilot study evaluated whether serum- and urine-derived microRNA (miRNA) …

Published: Nov. 26, 2025, midnight
The immunotherapy era in ovarian clear cell carcinoma: current evidence and future perspective.

Ovarian clear cell carcinoma (OCCC) is a rare, aggressive epithelial ovarian cancer subtype, accounting for approximately 10% of cases and associated with a poor prognosis due to chemoresistance and unique …

Published: Nov. 26, 2025, midnight
Appendiceal endometrioma mimicking appendiceal neoplasm.

Endometriosis of the vermiform appendix is an uncommon pathology that may present as an appendiceal mass identified on colonoscopy. This may be due to an appendiceal endometrioma or intussusception of …

Published: Nov. 25, 2025, midnight
Identifying serum microRNAs as biomarkers for endometriosis in adolescents and young adults.

Endometriosis is a gynecological disorder that affects 190 million reproductive age women worldwide. Laparoscopic surgery is considered the gold standard to diagnose the disease, creating a barrier to diagnosis and …

Published: Nov. 24, 2025, midnight
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