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Engineered Exosomes Restore miR-508-5p Expression in Uterine Corpus Endometrial Carcinoma and Reduce Tumor Progression and Metastasis by Targeting DLL3 - Frontiers

Engineered Exosomes Restore miR-508-5p Expression in Uterine Corpus Endometrial Carcinoma and Reduce Tumor Progression and Metastasis by Targeting DLL3 Frontiers

Published: Feb. 3, 2025, 2:27 p.m.
Association of Matrix Metalloproteinase-1 Promoter Genotypes With Endometriosis Risk.

Over-expression of matrix metalloproteinase-1 (MMP-1) has been suggested as a biomarker for endometriosis. However, the genetic influence of MMP-1 in the pathogenesis of endometriosis remains unclear, with its role yet …

Published: Feb. 3, 2025, midnight
Peritoneal Endometriosis Impairs Ovarian Reserve and Increases Atresia in a Rat Model.

Background/Objectives: Endometriosis has a marked impact on fertility, although the mechanisms behind this relationship remain poorly understood, particularly in cases without significant anatomical distortions or in the context of ovarian …

Published: Feb. 3, 2025, midnight
TRα1 mutant suppresses KLF9 to cause endometrial metaplasia with ectopic IL-33 expression leading to uterine fibrosis and infertility - Nature.com

TRα1 mutant suppresses KLF9 to cause endometrial metaplasia with ectopic IL-33 expression leading to uterine fibrosis and infertility Nature.com

Published: Jan. 31, 2025, 1:21 p.m.
Decreased expression of miR-200a and miR-223-3p in endometriosis during the secretory phase of menstrual cycle: Insights from a case-control study on molecular biomarkers and disease-related infertility.

Endometriosis (EM) is a condition that causes infertility with decreasing uterine receptivity. It is reported that it affects about 20-25% of all infertile women. Some genetic markers play a crucial …

Published: Jan. 31, 2025, midnight
Observational Data Challenge p53 Expression as a Surrogate Marker for TP53 Mutations in High-Risk Endometrial Cancer - OncLive

Observational Data Challenge p53 Expression as a Surrogate Marker for TP53 Mutations in High-Risk Endometrial Cancer OncLive

Published: Jan. 30, 2025, 10:29 p.m.
Potential value of novel multiparametric MRI radiomics for preoperative prediction of microsatellite instability and Ki-67 expression in endometrial cancer - Nature.com

Potential value of novel multiparametric MRI radiomics for preoperative prediction of microsatellite instability and Ki-67 expression in endometrial cancer Nature.com

Published: Jan. 25, 2025, 1:15 p.m.
Cyclooxygenase 2 overexpression suppresses Smad3 and augments ERK1/2 signaling activated by TGFβ1 in endometrial stromal cells: a novel insight into endometriosis pathogenesis.

To investigate the underlying mechanisms driving the opposing effects of transforming growth factor-beta 1 (TGFβ1) on the proliferation of control (CESCs) and ectopic (EESCs) endometrial stromal cells.

Published: Jan. 24, 2025, midnight
Identification of hub biomarkers and immune cell infiltrations participating in the pathogenesis of endometriosis.

Endometriosis (EM) is a chronic disease that can cause pain and infertility in patients. As is well known, immune cell infiltrations (ICIs) play important roles in the pathogenesis of EM. …

Published: Jan. 22, 2025, midnight
Neutrophils initiate pro-inflammatory immune responses in early endometriosis lesion development.

Endometriosis is a chronic gynecological disease that affects 1 in 10 reproductive-aged women. Most studies investigate established disease; however, the initiation and early events in endometriotic lesion development remain poorly …

Published: Jan. 21, 2025, midnight
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