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The long road of drug development for endometriosis - Pains, gains, and hopes.

Endometriosis, defined by the growth of endometrial tissues outside of the uterine cavity, is a global health burden for ~200 million women. Patients with endometriosis usually present with chronic pain …

Published: Oct. 18, 2024, midnight
Enhancing endometriosis care with telehealth: Opportunities and challenges.

Endometriosis affects a significant portion of women during their reproductive years, causing substantial pain and impacting their quality of life. Telehealth services have emerged as a promising avenue for enhancing …

Published: Oct. 16, 2024, midnight
Intravenous Magnesium for the Management of Chronic Pain:An Updated Review of the Literature.

Available therapeutic options are currently limited by their modest efficacy. As a result, novel pharmacotherapeutic treatments with different mechanisms have recently attracted empirical attention. Magnesium, a divalent cation, is postulated …

Published: Oct. 15, 2024, midnight
[Guideline for the diagnosis and treatment of endometriosis (Third edition)].

This is the third edition of guideline for the diagnosis and treatment of endometriosis in China. The second edition was published six years ago in 2015. It has been an …

Published: Oct. 14, 2024, 1:26 p.m.
A Pain Desensitization Algorithm for Phenotyping and Treating Chronic Pelvic Pain.

Chronic pelvic pain remains challenging for physicians to manage due to central and peripheral sensitization and multiple pain generators including the bladder, pelvic floor, and pudendal nerve. Pain management providers …

Published: Oct. 13, 2024, 4:36 p.m.
[Is there still a place for progesterone receptor modulators in chronic use ?].

Selective progesterone receptor modulators (SPRMs) are synthetic steroid compounds that interact with the progesterone receptor, inducing various agonist, antagonist or mixed responses. First identified with mifepristone, they are now represented …

Published: Oct. 13, 2024, 4:34 p.m.
Guidelines of the Polish Society of Gynecologists and Obstetricians on the management of women with endometriosis.

Published: Oct. 13, 2024, 4:32 p.m.
Patients with low prognosis in ART: a Delphi consensus to identify potential clinical implications and measure the impact of POSEIDON criteria.

Currently, there is no consensus on the optimal management of women with low prognosis in ART. In this Delphi consensus, a panel of international experts provided real-world clinical perspectives on …

Published: Oct. 10, 2024, midnight
Epidemiology of cardiovascular risk factors: Non-behavioural risk factors.

Cardiovascular disease is the leading cause of death worldwide, and the second leading cause in France. Among the modifiable cardiovascular risk factors, metabolic diseases (hypertension, low-density lipoprotein hypercholesterolaemia, diabetes and …

Published: Oct. 10, 2024, midnight
In vitro fertilization impact on the risk of breast cancer.

Breast cancer, with its increasing incidence and high mortality rates, remains a major global health challenge, significantly impacting individuals, families, and societies. Understanding the multifactorial risk factors contributing to its …

Published: Oct. 9, 2024, midnight
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