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Transcription factor addictions: exploring the potential Achilles' Heel of endometriosis.

A considerable number of women of reproductive age suffer from endometriosis worldwide. There is a significant physical, mental, and financial burden on patients affected by this condition in terms of …

Published: March 27, 2025, midnight
A novel senotherapeutic strategy with azithromycin for preventing endometriosis progression.

Endometriosis is an estrogen-dependent chronic inflammatory disease, however the mechanisms underlying inflammation remain unclear. Non-hormonal drugs that can prevent endometriosis progression and resolve endometriotic infertility are urgently required. We thus …

Published: March 26, 2025, midnight
A new perspective on endometriosis: Integrating eQTL mendelian randomization with transcriptomics and single-cell data analyses.

Endometriosis is caused by the migration of endometrial cells to locations outside the uterine lining. Despite the increasing prevalence of endometriosis, there has been limited research on genetic effects, and …

Published: March 26, 2025, midnight
Recent trends in the causation of peritoneal mesothelioma: fiber burden analysis of ten cases.

Mesothelioma in the past has been strongly associated with a history of asbestos exposure. Studies have shown that, on average, a higher dose of asbestos exposure is required for the …

Published: March 26, 2025, midnight
Endometriosis: assessment on O-RADS and risk of malignant transformation.

Endometriosis is a common disease, affecting approximately 10% of women of reproductive age. Several intersecting guidelines and consensus statements provide information on imaging diagnosis and surveillance strategies for endometriomas. SRU …

Published: March 26, 2025, midnight
Virtual reality-based pain control in endometriosis: a questionnaire-based pilot study of applications for relaxation and physical activity.

Virtual reality (VR) based technology may offer new avenues in the management of chronic endometriosis-related pain. Our prospective, 14-week, open, three-phase, cross-over pilot study investigated whether the use of VR …

Published: March 25, 2025, midnight
The Feasibility and Safety of Robot-Assisted Vaginal Natural Orifice Transluminal Endoscopic Surgery (RA-vNOTES) for Gynecologic Disease: 298-Case Series.

Objectives: To explore the feasibility and surgical outcomes of robot-assisted vaginal natural orifice transluminal endoscopic surgery (RA-vNOTES) for women suffering from gynecologic disease. Methods: We performed an observational study reporting …

Published: March 25, 2025, midnight
The Role of Exosomal miRNAs in Female Infertility: Therapeutic Potential and Mechanisms of Action.

Reproductive disorders, including preeclampsia (PE), endometriosis, premature ovarian failure (POF), and polycystic ovary syndrome (PCOS), present substantial challenges to women's reproductive health. Exosomes (EXOs) are cell-derived vesicles containing molecules that …

Published: March 24, 2025, midnight
Selective targeting of genes regulated by zinc finger proteins in endometriosis and endometrioid adenocarcinoma by zinc niflumato complex with neocuproine.

Inadequate angiogenesis of endometriotic implants stimulated by the inflammatory microenvironment in the uterine region leads to the development of gynecological diseases, which significantly reduce the fertility and vitality of young …

Published: March 24, 2025, midnight
Patients with endometriosis in the vagina, bowel, or bladder experience a prolonged diagnostic delay: an observational study.

Do the diagnostic delay and symptoms differ between endometriosis patients with advanced disease, defined as endometriosis involving the vagina, intestine, rectovaginal septum, or bladder (eVIRB), compared to patients without endometriosis …

Published: March 24, 2025, midnight
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