The immunology of fertilization, implantation and pregnancy is based on a complex balance between maternal immune tolerance and a controlled inflammatory response. Adaptation of the maternal immune system is essential …
Endometriosis (EM) is a persistent, chronic inflammatory condition associated with excruciating pelvic pain and infertility. The absence of a pre-clinical model that reliably replicates the clinical and functional hallmarks of …
Endometriosis (ENDO) is a chronic, estrogen-dependent condition affecting over 190 million females worldwide. Characterized by cyclic pelvic pain, infertility, and systemic inflammation, its symptoms profoundly impact quality of life, interfering …
This study aims to explore the genetic connection between inflammatory cytokines (IC) and endometriosis (EMs) to provide insights for the treatment of EMs.
Endometriosis is a chronic inflammatory condition experienced by approximately 10% of women worldwide. Women living with endometriosis experience multidimensional burdens often attributed to pain, fatigue, anxiety, and depression. Treatment patterns …
Women with endometriosis have a higher risk of developing inflammatory bowel diseases (IBD). This study aimed to better understanding the impact of endometriosis on the course of IBD.
In this opinion, we propose that compromised microvascular perfusion and inflammation are fundamental drivers of chronic pain syndromes, with many of these conditions sharing a common etiology involving suboptimal blood …
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used to alleviate pain associated with endometriosis (EMS), yet the impact of their long-term use on disease progression remains unclear. This study investigates the …
Endometriosis is a complex, chronic inflammatory gynecological disorder with estrogen‑dependent characteristics that severely impairs the quality of life of women and potentially leads to infertility. However, its pathogenesis remains poorly …
Endometriosis (EM) is a chronic inflammatory disorder characterized by the growth of ectopic endometrial-like tissue and fibrosis. Metabolic reprogramming, particularly enhanced glycolysis, and immune microenvironment dysregulation are key features of …