Arimoclomol-loaded Pluronic F127 nanomicelles in experimental endometriosis: drug incorporation, in vitro release, and early morphological and histological responses.
Endometriosis is a chronic, estrogen-dependent inflammatory disease characterized by ectopic endometrial-like glands and stroma, persistent pelvic inflammation, pain, infertility, and frequent recurrence. The limited availability of nonhormonal and lesion-directed therapies …
Clinical Characteristics of Unilateral versus Bilateral Ovarian Endometriomas and Risk Stratification in Stage IV Disease Using the rASRM Score: A Retrospective Cohort Study from a Tertiary Medical Center.
Endometriomas are a common manifestation of endometriosis and can present as unilateral or bilateral disease. While bilateral involvement is clinically suspected to reflect more severe disease and greater impairment of …
Establishment of pathology-validated immortalized patient-derived ovarian endometriosis epithelial cell line.
Endometriosis is a heterogeneous gynecological disorder for which experimental model development is often limited by diagnostic ambiguity and the restricted lifespan of primary epithelial cultures. Although immortalization strategies enable long-term …
Prediction models for endometriosis-associated ovarian malignancy: A systematic review and meta-analysis.
Endometriosis is benign, but it is associated with an increased risk of clear-cell and endometrioid ovarian carcinoma. Several multivariable prediction models have been developed to identify malignant transformation or differentiate …