The pharmacological treatment of endometriosis using SPRMs requires improvement. The pure PR-agonist dienogest (DNG), a clinically established progestin, can serve as a reference compound for comparison. Its efficacy and safety …
Endometriosis is an estrogen-dependent chronic systemic inflammatory disease that affects 10 % of people assigned female at birth. Despite its prevalence, mean diagnostic delay is 4-11 years. Although much research …
Endometriosis and uterine leiomyomas are common chronic gynecologic diseases associated with immune dysregulation, inflammation and aberrant cellular proliferation, processes that contribute to increased oxidative stress. Current management relies largely on …
To evaluate the incidence of voiding dysfunction (VD) after surgery for deep infiltrating endometriosis (DIE) with colorectal involvement and to compare outcomes between conventional laparoscopy (CL) and robotic-assisted laparoscopic surgery …
Alcohol sclerotherapy has been shown to reduce endometrioma recurrence and improve ovarian response, including the number of retrieved oocytes and antral follicle count (AFC), compared with surgical cystectomy. This randomized …
This study aimed to summarize the clinical characteristics, surgical management, and follow-up outcomes of patients with severe renal impairment caused by ureteral endometriosis.
Endometriosis is a chronic, estrogen-dependent inflammatory disorder marked by ectopic endometrial-like tissue growth, resulting in pelvic pain, infertility, and significant declines in quality of life. Despite extensive research, current therapies …
The uterus is an essential organ for fetal development in most mammals. Uterine glands, highly conserved structures in the mammalian uterus, play critical roles in the establishment and maintenance of …
We examined clinical, genetic, and molecular links between sleep disorders and endometriosis. Women aged 20-54 years in NHANES 2005-2006 were analyzed with survey-weighted logistic regression. Bidirectional two-sample Mendelian randomization (MR) …
Endometriosis is a highly prevalent and morbid condition in women of reproductive age, often leading to well-known complications such as infertility, intestinal adhesions, and severe chronic pelvic pain. There is …