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NXF1 suppresses progression of endometrial cancer by interacting with the SRSF3 to regulate SP4 splicing.

Conventional treatments for advanced endometriosis often have limited efficacy due to chemotherapy resistance, recurrence, and metastasis. This study analyzed clinical specimens to investigate the role of NXF1 in endometrial cancer …

Published: July 22, 2025, midnight
The Effect of Dienogest on Deep Endometriosis Nodules Involving the Recto-Sigmoid Colon: A Prospective Longitudinal Long-Term Study.

Objective: To assess the long-term effects of Dienogest on clinical complaints and nodule sizes in women affected by recto-sigmoid deep endometriosis (DE). Methods: This was a single-center longitudinal prospective observational …

Published: July 21, 2025, midnight
Parexel Supports GLP-1 Trials for Metabolic Disorders as Eisai Investigates Dual-Mechanism Therapy for Endometrial Carcinoma - geneonline.com

Parexel Supports GLP-1 Trials for Metabolic Disorders as Eisai Investigates Dual-Mechanism Therapy for Endometrial Carcinoma geneonline.com

Published: July 18, 2025, 11:05 a.m.
Exploring the Promise of E7386 and Lenvatinib Combination Therapy in Endometrial Carcinoma - PharmExec

Exploring the Promise of E7386 and Lenvatinib Combination Therapy in Endometrial Carcinoma PharmExec

Published: July 18, 2025, 10:08 a.m.
Eisai Explores Novel Dual Mechanism Therapy for Advanced Endometrial Carcinoma - PharmExec

Eisai Explores Novel Dual Mechanism Therapy for Advanced Endometrial Carcinoma PharmExec

Published: July 17, 2025, 10:09 a.m.
Non-Hormonal Strategies in Endometriosis: Targets with Future Clinical Potential.

Endometriosis is a chronic gynecological pathology marked by the aberrant proliferation of tissue analogous to the endometrial lining outside the uterine cavity. This disorder frequently engenders persistent pelvic discomfort, infertility, …

Published: July 17, 2025, midnight
Exploring the therapeutic potential of H1-antihistamines in endometriosis-A gene regulation-based perspective.

Recent studies emphasize the role of immune dysregulation and inflammation in endometriosis (ES). While hormonal therapy remains the primary treatment, emerging research is exploring synergistic approaches that target inflammation. In …

Published: July 17, 2025, midnight
Advanced Ovarian and Endometrial Cancers Respond to Combination Immunotherapy - Labroots

Advanced Ovarian and Endometrial Cancers Respond to Combination Immunotherapy Labroots

Published: July 14, 2025, 10 a.m.
Disease Severity- and Hormonal Status-Dependent Alterations of EGF and MIF in the Serum of Endometriosis Patients.

Endometriosis is the extrauterine engraftment of endometrium-like tissue, causing chronic pain. Complex sensory-vascular-immune interactions, including growth factors, cytokines, and neuropeptides, are implicated in its pathophysiology, but the mechanisms remain unknown. …

Published: July 12, 2025, midnight
Dostarlimab Plus Chemo Prolongs Time to First, Second Subsequent Therapy Regardless of Age in Endometrial Cancer - OncLive

Dostarlimab Plus Chemo Prolongs Time to First, Second Subsequent Therapy Regardless of Age in Endometrial Cancer OncLive

Published: July 11, 2025, 6:17 p.m.
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