Endometriosis, a common chronic gynecological disorder, involves cellular autophagy and inflammatory processes in its pathogenesis. However, the specific regulatory mechanisms of autophagy and inflammation in endometriosis remain unknown. In this …
Several hypotheses have been proposed to explain the establishment of endometriosis, of which retrograde menstruation remains the most widely accepted mechanism of dissemination. However, the mechanisms governing selective lesion establishment …
Endometriosis (EMs) is characterized by ectopic lesions that disrupt endometrial decidualization, a process frequently accompanied by aberrant collagen deposition and closely linked to clinical infertility. Extracellular vesicles (EVs) are key …
The link between endometriosis and other medical conditions is gaining attention. Such insights could enhance clinical approaches to manage the disease and potentially reveal new, unrecognized mechanisms of its development. …
The human endometrium is a complex, dynamic and poorly understood tissue involving monthly cyclical regeneration likely from adult stem/progenitor cells. This regeneration is associated with reproductive pathologies, such as endometriosis …
Fibroblast growth factor receptor 2 (FGFR2) has emerged as a highly promising therapeutic target due to its critical role in the pathogenesis and progression of endometriosis. To date, a variety …
Clear cell carcinoma arising from abdominal wall endometriosis is an exceptionally rare malignancy that typically develops at prior surgical scar sites. We report a case of a woman in her …
To investigate the mechanisms of histone deacetylase (HDAC) 10 inhibitors (HDAC10Is) action in endometriosis and the target molecules of HDAC10Is.