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Endometriosis: cannabidiol therapy for symptom relief.

Endometriosis is a common, chronic, incurable condition the hallmark of which is the presence of lesions (tissue resembling endometrium) in sites outside the womb, with symptoms including chronic debilitating pain …

Published: Nov. 14, 2024, midnight
Endometriosis: Future Biological Perspectives for Diagnosis and Treatment.

Endometriosis is an oestrogen-dependent inflammatory disease affecting menstruating women, with varying levels of severity. Oestrogen dysregulation is responsible for chronic inflammation, angiogenesis, endometrial lesion development, progression, and infertility during menarche …

Published: Nov. 14, 2024, midnight
Autophagy Involvement in Non-Neoplastic and Neoplastic Endometrial Pathology: The State of the Art with a Focus on Carcinoma.

Autophagy is a cellular process crucial for maintaining homeostasis by degrading damaged proteins and organelles. It is stimulated in response to stress, recycling nutrients and generating energy for cell survival. …

Published: Nov. 12, 2024, midnight
The Critical Role of Host and Bacterial Extracellular Vesicles in Endometriosis.

Endometriosis is a chronic, inflammatory, oestrogen-dependent disorder that is defined by the presence of endometrium-like tissue in the extra-uterine environment. It is estimated to affect approximately 10% of women of …

Published: Nov. 12, 2024, midnight
Associations between stigma and depression among college-attending women with endometriosis symptoms.

Background: Endometriosis is a debilitating and highly stigmatized chronic condition. The relationship between stigma and depressive symptoms among college-attending women with endometriosis symptoms was examined. Method: Data were analyzed from …

Published: Nov. 8, 2024, midnight
[Exploring non-hormonal therapies and drug repositioning for endometriosis: insights from mouse model studies].

The mainstay of treatment for endometriosis is hormonal therapy, which suppresses ovulation; therefore, patients cannot conceive during treatment. There is a dilemma with ovarian-sparing surgery, known as laparoscopic cystectomy, as …

Published: Nov. 6, 2024, midnight
[Fibrosis signaling in endometrial cells and endometriosis development].

In endometriosis, the tissues similar to the endometrial tissue attaches outside the uterine cavity, causing inflammation and fibrosis. The retrograde menstruation theory is the most plausible mechanism, though the detailed …

Published: Nov. 6, 2024, midnight
[Current and future medical treatment for endometriosis].

Endometriosis is a chronic, progressive inflammatory disease that occurs in approximately 10% of women of reproductive age, resulting in a decreased quality of life due to dysmenorrhea, chronic pain, and …

Published: Nov. 6, 2024, midnight
Nociceptor-to-macrophage communication through CGRP/RAMP1 signaling drives endometriosis-associated pain and lesion growth in mice.

Endometriosis is a debilitating and painful gynecological inflammatory disease affecting up to 15% of women and transgender men. Current treatments are ineffective for a substantial proportion of patients, underscoring the …

Published: Nov. 6, 2024, midnight
Digital Twin of the Female Pelvic Floor.

Digital twin technology, originally developed for intricate physical systems, holds great potential in women's healthcare, particularly in the management of pelvic floor disorders. This paper delves into the development of …

Published: Nov. 6, 2024, midnight
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