The extracellular matrix (ECM) critically influences cell behavior, yet its properties in human endometrial lesions (HEL) and human uterine fibromas (HUF) are not well characterized. This study aimed to characterize …
This study aimed to compare clinical and ultrasound outcomes over 24 months in premenopausal women with ultrasound-diagnosed endometriosis/adenomyosis, never treated surgically, and managed with or without hormonal therapy. We specifically …
Deep endometriosis (DE) is established to cause chronic pelvic pain (CPP), lower urinary tract symptoms (LUTS) and altered bowel function. Although the aim of surgical excision is often to relieve …
Endometriosis is a chronic gynecological disorder characterized by ectopic endometrial tissue, commonly affecting pelvic structures. Rarely, it occurs in extrapelvic locations, mimicking other pathologies and posing diagnostic challenges.
The AFF2 gene encodes a protein involved in transcriptional regulation and chromatin remodeling. While primarily associated with Fragile X syndrome, AFF2 fusions have recently been identified in certain malignancies, mostly …
The genotype of our cells is almost the same for all cells in our body, but due to epigenetic effects, their phenotype can show significant differences. Epigenetics is a relatively …
This study aimed to investigate the causal relationship between dietary habits and nine common diseases with high female prevalence using a two-sample Mendelian randomization (MR) approach.
Appendiceal endosalpingiosis is an exceedingly rare histopathologic finding with uncertain clinical significance and unknown implications for management. Most often, endosalpingiosis occurs within ovary, fallopian tube, omentum, and uterus. Previous literature …