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[Efficacy and safety of triptorelin acetate microspheres for injection versus triptorelin acetate for injection in Chinese patients with endometriosis: a multicenter, randomized, double-blind, phase Ⅲ non-inferiority clinical trial].

Objective: To evaluate the efficacy and safety of triptorelin acetate microspheres for injection compared with triptorelin acetate for injection in the treatment of endometriosis. Methods: A total of 392 patients …

Published: Jan. 31, 2026, midnight
Etiology and Risk Factors of Infertility Among Omani Couples: A Retrospective Study from a Tertiary Referral Center.

This study aimed to investigate the etiology and risk factors of infertility among Omani couples aged 18-49 years.

Published: Jan. 31, 2026, midnight
Epigenetic Mechanisms of Reproductive Dysfunction Induced by Endocrine-Disrupting Chemicals: Evidence From Molecular Studies.

Endocrine-disrupting chemicals (EDCs), including bisphenol A (BPA), phthalates, organochlorine pesticides, and heavy metal ions, pose serious threats to reproductive health by interfering with hormonal balance and molecular signaling pathways. Recent …

Published: Jan. 30, 2026, midnight
Associations of Lipid Metabolism Abnormalities and Obesity With Endometriosis-Associated Ovarian Cancer.

To investigate the differences in lipid metabolism and obesity between patients with ovarian endometrioid carcinoma (OEC) and ovarian clear cell carcinoma (OCCC), both of which are classified as endometriosis-associated Type …

Published: Jan. 30, 2026, midnight
Barriers affecting medication adherence to dienogest among patients with ovarian endometriosis: a qualitative study.

To explore barriers affecting medication adherence (e.g., missed doses, forgotten doses, or discontinuation) among patients with Ovarian Endometriosis (OE) using the Capability, Opportunity, Motivation - Behaviour (COM-B) behavioural change model …

Published: Jan. 30, 2026, midnight
Rethinking estrogen receptor β in EAOC: a synergistic modulator in a genomically informed landscape.

Published: Jan. 27, 2026, midnight
HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma.

Ovarian clear cell carcinoma (CCC) is an aggressive subtype of ovarian cancer that is resistant to conventional chemotherapy, resulting in poor prognosis. CCC develops from endometriosis, which exposes tumor cells …

Published: Jan. 27, 2026, midnight
Metabolism-Regulating Microspheres: Design Principles, Therapeutic Applications Across Multisystem Diseases, and Future Perspectives.

Metabolism-regulating microspheres have evolved from conventional drug carriers into active platforms capable of spatiotemporally reprogramming pathological metabolic networks. Chronic diseases are increasingly understood to be driven by metabolic dysregulation, highlighting …

Published: Jan. 27, 2026, midnight
Beneficial Effects of Fisetin, a Senotherapeutic Compound, in Women's Reproductive Health and Diseases: Evidence from In Vitro to Clinical Studies.

Fisetin is a naturally occurring flavonoid, a type of polyphenol found in fruits and vegetables such as strawberries, apples, persimmons, and onions. It has gained increasing attention for its antioxidant …

Published: Jan. 25, 2026, midnight
Optimal Laparoscopic Surgical Technique for Preserving Fertility and Ovarian Reserve in Patients with Endometrioma: A Systematic Review and Bayesian Network Meta-Analysis of Randomized Controlled Trials.

This systematic review and Bayesian network meta-analysis aimed to evaluate the comparative efficacy and safety of various laparoscopic techniques for endometrioma management, focusing on their impact on fertility outcomes and …

Published: Jan. 24, 2026, midnight
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