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Is endometriosis staging related to the type and intensity of patients' complaints? A systematic review and meta-analysis.

To evaluate the association between the endometriosis staging and the type and intensity of pain reported by patients, describing the pain intensity across different pain types.

Published: Dec. 1, 2025, midnight
From Mice to Primates: Assessing Hormone-Based Endometriosis Models for Preclinical and Therapeutic Insights.

Endometriosis, a complex gynecological disorder characterized by ectopic endometrial-like tissue, affects over 10% of women, causing chronic pain and infertility. Despite extensive research, its pathophysiology remains incompletely understood, with proposed …

Published: Dec. 1, 2025, midnight
Endometriosis in Carriers of a Pathogenic Variant in BRCA1 or BRCA2: A Descriptive Analysis of a Large Multicentral BRCA Carrier Cohort.

Background: Endometriosis affects an estimated 10% of reproductive-aged women and is associated with increased ovarian cancer risk. While BRCA1/2 mutations are established risk factors for ovarian cancer, their association with …

Published: Dec. 1, 2025, midnight
Biochemical Heterogeneity of Endometriosis Phenotypes Revealed by FTIR Analysis.

Fourier-transform infrared (FTIR) spectroscopy was used to investigate molecular differences among peritoneal, ovarian, bowel endometriosis phenotypes and control tissues. Peritoneal lesions showed the most pronounced spectral changes in CH-stretching (2800-3000 …

Published: Nov. 30, 2025, midnight
Deep endometriosis: evaluation of ENZIAN and #ENZIAN classification systems by MRI compared with surgery-a meta-analysis.

To assess the reproducibility and the diagnostic accuracy of MRI for the assessment of (#)ENZIAN classification in patients with deep endometriosis by means of a meta-analysis.

Published: Nov. 29, 2025, midnight
Exploring the impact of dietary theobromine on endometriosis risk: Evidence from Mendelian randomization and NHANES data.

Endometriosis is a chronic inflammatory estrogen-dependent inflammatory disorder. Theobromine has been implicated in diverse health benefits, including anti-inflammatory and vasodilatory properties. However, the precise association between theobromine and endometriosis remains …

Published: Nov. 28, 2025, midnight
Dienogest Therapy Against the Combined Oral Contraceptive Pill in Deep Infiltrating Endometriosis Cases: A Systematic Review and Meta-Analysis.

Deep endometriosis (DE) is a common disease in 15%-45% of childbearing-age women. Combined oral contraceptive pill (COCP) and dienogest have been used for decades to treat many forms of endometriosis …

Published: Nov. 28, 2025, midnight
Integrating inflammatory biomarkers and demographic variables with machine learning to predict endometriosis risk.

This study explores the relationship between inflammatory biomarkers and the risk of endometriosis, aiming to develop a predictive model using National Health and Nutrition Examination Survey (1999-2006) data. The dataset …

Published: Nov. 27, 2025, midnight
Risk of cardiovascular disease and mortality among women with endometriosis: A systematic review and meta-analysis.

Endometriosis is a chronic and estrogen-dependent disorder that affects about 10% of women of reproductive age worldwide. Endometriosis has been associated with chronic inflammation and an atherogenic lipid profile, two …

Published: Nov. 27, 2025, midnight
Appendiceal endometriosis: an uncommon manifestation of deep infiltrating endometriosis.

Appendiceal endometriosis is a rare cause of acute appendicitis, accounting for approximately 1% of cases.This report describes a case of a female patient presenting with right iliac fossa pain and …

Published: Nov. 26, 2025, midnight
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