Nearly a century has passed since a seminal review article was published in 1928 in Archives of Pathology on ectopic endometriosis, presenting the dominant pathogenetic theories of the era: the …
Gonadotropin-releasing hormone (GnRH) antagonists inhibit estrogen synthesis and secretion, making them promising treatment options for estrogen-dependent diseases, such as endometriosis. This study developed a population pharmacokinetic/pharmacodynamic (PK/PD) model for merigolix, …
Endometriosis (EM) affects approximately 10% of women of reproductive age and remains a prevalent estrogen-dependent gynecological disorder with limited therapeutic efficacy and high recurrence rates. Ferroptosis-an iron-dependent, non-apoptotic form of …
Endometriosis is a chronic inflammatory disorder that affects approximately 10% of women of reproductive age and exhibits tumor-like characteristics such as invasion, recurrence, and hormone-dependent proliferation despite its benign nature. …
The objective of this review is to identify key clinical lessons and highlight diagnostic and therapeutic strategies derived from case reports and recent literature. Particular attention is given to recognising …
For many patients with endometriosis, laparoscopic surgery is the most effective treatment to alleviate severe chronic pelvic pain and improve quality of life. Because endometriosis is common among individuals with …
Endometriosis, which affects approximately 10% of women of reproductive age, is a complex inflammatory disease with significant immune system disturbances caused by an inadequate immune response to retrograde menstruation and …
Endometriosis is a condition affecting approximately 10% of reproductive-age women in which endometrial tissue is found in locations outside the uterus, often causing debilitating symptoms. Aromatase, an enzyme that also …
Traumatic separation of the cervix from the body of the uterus is exceedingly rare, particularly as a complication of pelvic fractures. This condition often poses significant diagnostic and therapeutic challenges, …
Deep infiltrating endometriosis (DIE) is a severe condition frequently linked to infertility, yet the optimal integration of surgery and assisted reproductive technology (ART) remains controversial. This study reports two cases …