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Bioinformatical analysis of the key differentially expressed genes and associations with immune cell infiltration in development of endometriosis.

This study explored the key genes related to immune cell infiltration in endometriosis.

Published: March 18, 2022, midnight
Insights Into the Regulation of Gynecological Inflammation-Mediated Malignancy by Metalloproteinases.

Gynecological illness accounts for around 4.5% of the global disease burden, which is higher than other key global health concerns such as malaria (1.04%), TB (1.9%), ischemic heart disease (2.2%), …

Published: Nov. 29, 2021, midnight
Placenta Previa Complicated with Endometriosis: Contemporary Clinical Management, Molecular Mechanisms, and Future Research Opportunities.

Endometriosis is a common gynecological disease characterized by chronic inflammation, with an estimated prevalence of approximately 5-15% in reproductive-aged women. This study aimed to assess the relationship between placenta previa …

Published: Oct. 26, 2021, midnight
Human Exposure to Polychlorinated Biphenyls (PCBs) and The Risk of Endometriosis: A Systematic Review and Meta-Analysis Protocol.

Endometriosis is one of the gynecological disorders and its prevalence is estimated to 8.10% of reproductive-age women. In Iran, the frequency of endometriosis was reported at 29% among infertile women. …

Published: Sept. 21, 2021, midnight
Genetic and Epidemiological Similarities, and Differences Between Postoperative Intraperitoneal Adhesion Development and Other Benign Fibro-proliferative Disorders.

Intraperitoneal adhesions complicate over half of abdominal-pelvic surgeries with immediate, short, and long-term sequelae of major healthcare concern. The pathogenesis of adhesion development is similar to the pathogenesis of wound …

Published: Sept. 13, 2021, midnight
Exosomal lncRNA CHL1-AS1 Derived from Peritoneal Macrophages Promotes the Progression of Endometriosis via the miR-610/MDM2 Axis.

Exosomes secreted by peritoneal macrophages (pMφ) are deeply involved in the development of endometriosis (EMs). Exosomes can mediate cell-to-cell communication by transferring biological molecules. This study aimed to explore the …

Published: Aug. 12, 2021, midnight
Identification and Exploration of Novel Macrophage M2-Related Biomarkers and Potential Therapeutic Agents in Endometriosis.

Endometriosis (EM) is a chronic neuroinflammatory disorder that is associated with pain and infertility that affects ∼10% of reproductive-age women. The pathophysiology and etiology of EM remain poorly understood, and …

Published: July 6, 2021, midnight
Functional changes of immune cells: signal of immune tolerance of the ectopic lesions in endometriosis?

What is the potential role of immune cells and their inflammatory cytokines in the pathogenesis, development and establishment of endometriosis?

Published: April 24, 2021, midnight
MiR-370-3p inhibits the development of human endometriosis by downregulating EDN1 expression in endometrial stromal cells.

MiR-370-3p has been demonstrated to be downregulated in patients with endometriosis (EM). However, its role and molecular mechanisms in the progression of EM remain unclear. Real-time polymerase chain reaction was …

Published: March 26, 2021, midnight
Ameliorating Effects of Natural Antioxidant Compounds on Female Infertility: a Review.

The prevalence of female infertility cases has been increasing at a frightening rate, affecting approximately 48 million women across the world. However, oxidative stress has been recognized as one of …

Published: Sept. 15, 2020, midnight
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