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Pro-endometriosis macrophage release of IL-33 is key for endometriosis pain and lesion formation.

Endometriosis is a painful gynecological inflammatory disease affecting up to 10% of females. When released by sensory neurons, calcitonin gene-related peptide (CGRP) shapes immunity, a process known as neuroimmune communication. …

Published: Oct. 21, 2025, midnight
Shaoyao Gancao Decoction: a comprehensive review of modern clinical applications and underlying pharmacological mechanisms.

Shaoyao Gancao Decoction, a classic formula from Zhang Zhongjing in the Han Dynasty, has the effects of regulating the function of the liver, relieving spasm and stopping pain. Traditionally, it …

Published: Oct. 20, 2025, midnight
Cellular Senescence in Endometrium: A Pivotal Regulator in Physiological Remodeling and Pathological Disorders.

As a highly dynamic tissue, the endometrium undergoes complex remodeling during the menstrual cycle and pregnancy. Recent studies have revealed that cellular senescence plays a pivotal role in both physiological …

Published: Oct. 20, 2025, midnight
Depression and anxiety in patients with endometriosis-associated chronic pain: Neuroimmune mechanisms mediated by inflammatory factors.

Endometriosis affects approximately 10% of reproductive-age women and is frequently associated with chronic pelvic pain. Patients with endometriosis often experience comorbid depression and anxiety, but the underlying mechanisms connecting these …

Published: Oct. 19, 2025, midnight
Diagnostic utility of Synuclein gamma (SNCG) and b-cell Lymphoma 6 (BCL6) as potential non-invasive dual biomarkers for endometriosis.

This pilot study evaluated Synuclein gamma (SNCG) and B-Cell Lymphoma 6 (BCL6) proteins as potential non-invasive biomarkers in serum and menstrual fluid (MF) to differentiate endometriosis patients from non-endometriosis and …

Published: Oct. 19, 2025, midnight
[Endometriosis management in the emergency department: a diagnostic and therapeutic challenge].

Endometriosis affects at least one in ten women of childbearing age, yet it is often overlooked in emergency care. Clinicians should consider this diagnosis for any woman presenting with menstrual …

Published: Oct. 18, 2025, midnight
From Innovation to Impact: Mesentery-Sparing NOSE Surgery for Bowel Endometriosis.

Published: Oct. 18, 2025, midnight
Addressing Meta-Inflammation in the Comprehensive Management of Chronic Pain.

Chronic pain is a widespread condition affecting millions globally, placing significant strain on healthcare systems, as evidenced by the current opioid crisis. Despite advances in pain management, conventional treatments often …

Published: Oct. 18, 2025, midnight
Catamenial Pneumothorax Without Thoracic Endometriosis: A Case Report From the Gulf Cooperation Council (GCC) Region.

Catamenial pneumothorax is a rare clinical condition first described over seven decades ago. It typically occurs within 72 hours before or after menstruation and is most frequently observed in women …

Published: Oct. 18, 2025, midnight
Integrating Thyroid Autoantibodies With CA125 Enhances Diagnostic Precision for Ovarian Endometriosis: A Retrospective Study of 885 Patients.

This study aimed to compare clinical characteristics and evaluate diagnostic biomarkers in ovarian endometriosis, with a focus on thyroid autoimmunity associations.

Published: Oct. 17, 2025, midnight
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