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NLRP3 Inflammasome in Gynecologic Inflammatory Diseases: Mechanisms, Pathophysiology, and Therapeutic Strategies.

The NOD-like receptor family containing pyridine domain 3 (NLRP3) inflammasome serves as a pivotal mediator of innate immune responses and a central driver of inflammatory processes. Upon detection of pathogenic …

Published: Oct. 10, 2025, midnight
The Diagnostic Performance of Transvaginal Ultrasound for Posterior Compartment Endometriosis Compared to Laparoscopic and Histopathological Findings: A Systematic Review.

Background: Deep infiltrating endometriosis (DIE) frequently affects the posterior pelvic compartment, where accurate non-invasive imaging is essential for diagnosis and surgical planning. Aim: This systematic review evaluates the diagnostic performance …

Published: Oct. 10, 2025, midnight
Progestagens for pain symptoms associated with endometriosis.

Endometriosis is a hormone-sensitive inflammatory condition affecting between 5% and 10% of reproductive-aged women and an unknown number of gender-diverse individuals. It is often associated with debilitating pelvic pain symptoms. …

Published: Oct. 9, 2025, midnight
Minimal clinically important changes of patient-reported outcome measures for acute post-surgical pain.

Patient-Reported Outcome Measures (PROMs) are essential instruments for assessing post-surgical pain-related outcomes from the patient's perspective. The concept of minimal clinically important difference (MCID) aims to identify the smallest change …

Published: Oct. 9, 2025, midnight
Comparison of the short-term effects of dienogest and oral contraceptives on pain and quality of life in women with endometriosis: a systematic review and meta-analysis.

To compare the short-term effects of dienogest and oral contraceptives (OCPs) on pain and quality of life in women with endometriosis.

Published: Oct. 9, 2025, midnight
Risk of endometriosis, adenomyosis and related symptoms among female offspring according to conception by assisted reproductive technologies.

To study the relationship between conception by ART and risk of endometriosis/adenomyosis in female offspring.

Published: Oct. 9, 2025, midnight
Plant-based bioactives and oxidative stress in reproduction: anti-inflammatory and metabolic protection mechanisms.

Oxidative stress plays a central role in reproductive disorders, with food bioactive compounds offering therapeutic potential through their antioxidant properties. This review examines antioxidant active ingredients from plant-based foods and …

Published: Oct. 9, 2025, midnight
Identification and Validation of Iron Metabolism-Related Biomarkers in Endometriosis: A Mendelian Randomization and Single-Cell Transcriptomics Study.

Studies have shown that the iron concentration in the peritoneal fluid of women is associated with the severity of endometriosis. Therefore, investigation of iron metabolism-related genes (IM-RGs) in endometriosis holds …

Published: Oct. 9, 2025, midnight
Whispers of the Lungs: Unraveling the Mystery of Catamenial Pneumothorax.

Catamenial pneumothorax (CP) is an uncommon condition marked by recurrent spontaneous pneumothorax in women, typically occurring within the first 72 hours of menstruation. It is also the most prevalent manifestation …

Published: Oct. 9, 2025, midnight
Pain, Emotions, Interoception, and Bodily Sensations in Patients With Endometriosis Bodily Sensations in Patients With Endometriosis.

Psychosocial aspects underlie and maintain persistent pain. Emotions have emerged as a target for psychological interventions in pain management. Our aim was to better understand the relationship between emotions and …

Published: Oct. 8, 2025, midnight
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