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The Circadian-Light-Hygiene Hypothesis: A Potential Modulator of Fertility and Birthrate Trends.

Human fertility has declined sharply since 1950, and a growing body of evidence suggests that while conventional socioeconomic factors are well-established drivers of the broader demographic transition, they do not …

Published: June 26, 2026, midnight
Hyaluronic Acid Enriched Medium for Embryo Transfer: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis of randomized controlled trials (RCTs) evaluated whether the use of hyaluronic acid (HA)-enriched medium for embryo transfer (ET) improves live birth rates in in-vitro fertilization …

Published: June 23, 2026, midnight
Fertility-sparing strategy in a rare case of uterine adenosarcoma and consecutive spontaneous pregnancy and livebirth.

We present the rare case of a 29-year-old patient with uterine adenosarcoma who received fertility-sparing treatment, subsequently conceived spontaneously, and gave birth to a healthy infant.

Published: June 23, 2026, midnight
Incidence and remission of endometriosis in Germany based on prevalence data from 35 million patients from the statutory health insurance.

Endometriosis is a chronic gynecological disease that can potentially develop as early as birth and can restrict the life of the patient. With the increasing prevalence of endometriosis in Germany, …

Published: June 23, 2026, midnight
Natural versus artificial cycle for endometrial preparation in ovulatory women undergoing frozen-thawed embryo transfer: a randomised controlled trial.

Does a natural cycle result in higher clinical pregnancy rates (CPR) with foetal heartbeat compared to an artificial cycle for frozen-thawed embryo transfer (FET) preparation in ovulatory women?

Published: June 19, 2026, midnight
The female reproductive tract microbiotas, inflammation, and gynecological conditions: mechanisms, therapeutic advances, and future perspectives.

The female reproductive tract (FRT), particularly the vagina, has traditionally been regarded as a sterile environment. However, it is now recognized that the vagina is a complex, dynamic ecosystem dominated …

Published: June 16, 2026, midnight
Predicting natural conception leading to live birth for couples with infertility: a single-centre population-based cohort study of 7086 couples.

Can a model be developed to predict natural conception leading to live birth over a period of 12 months in couples with different causes of infertility?

Published: June 13, 2026, midnight
Endometriosis-Associated Infertility: A Review of Pathophysiological Mechanisms and Current Treatment Strategies.

Background: Endometriosis affects 10-15% of reproductive-aged women and is a leading cause of infertility through anatomical, inflammatory, and molecular mechanisms. Objective: This review synthesizes current evidence on the pathophysiology of …

Published: June 2, 2026, midnight
Endometrial BCL6 Expression and Reproductive Outcomes in Infertile Women: A Systematic Review.

Background/Objectives: Endometrial B-cell lymphoma 6 (BCL6) overexpression has been proposed as a marker of progesterone resistance, occult endometriosis, and endometrial dysfunction in infertile women. Its possible association with reproductive outcomes …

Published: June 2, 2026, midnight
Comparable live births for single vitrified blastocyst transfer from day 5 compared with day 6: a retrospective analysis.

Do blastocysts vitrified on day 6 result in different clinical outcomes compared with blastocysts vitrified on day 5 in vitrified‒warmed single embryo transfers (SET) without preimplantation genetic testing?

Published: May 26, 2026, midnight
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