Early diagnosis of ovarian cancer remains one of the most important unmet needs in gynecologic oncology because survival is strongly stage-dependent and most patients still present with disseminated disease. Conventional …
This study aims to elucidate the molecular mechanisms underlying luteolin's therapeutic effects on polycystic ovary syndrome (PCOS) and endometriosis (EM), thereby providing a theoretical foundation for developing novel treatment strategies. …
Photoacoustic imaging (PAI) is an emerging hybrid biomedical imaging modality that combines the high molecular contrast of optical excitation with the deep tissue penetration of ultrasound detection. This review presents …
Endocrine-disrupting chemicals (EDCs) are a global concern for human health and the environment. EDCs include plasticizers, pharmaceutical agents, industrial chemicals, fungicides, and pesticides. Thus, EDC exposure is a manmade consequence …
Endometriosis (EM) is a chronic, estrogen-dependent disease that lacks reliable noninvasive diagnostic biomarkers. This study was aimed at evaluating the diagnostic value of PAX8 using integrated transcriptomic and machine learning …
Hysterectomy is a commonly performed gynecological surgery for conditions such as uterine fibroids, endometriosis, and abnormal uterine bleeding. However, the procedure provides therapeutic benefits, its increasing prevalence at older reproductive …
Gynecological diseases represent a persistent global health burden. According to a WHO report, the global incidence of gynecological diseases exceeds 65%. Furthermore, over 90% of women suffer from gynecological issues …
The fundamental mechanisms behind the causes and development of endometriosis are still poorly understood. Therefore, identifying biomarkers that can help with early detection and targeted treatment is crucial for effective …
This study aimed to evaluate the potential causal association between obstructive sleep apnea (OSA) and the risk of female reproductive endocrine diseases (REDs), including polycystic ovary syndrome (PCOS), endometriosis (EMs), …
Endometriosis is increasingly recognized as a disorder of impaired reproductive immune tolerance rather than solely an endocrine disease. Although previous studies have reported inconsistent findings regarding the number of regulatory …