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Adjunctive vitamin D supplementation in women receiving dienogest therapy for endometriosis: a randomized controlled trial.

Endometriosis is a chronic, estrogen-dependent inflammatory disease that causes debilitating pain and significantly impairs quality of life. Due to its anti-inflammatory and immunomodulatory properties, vitamin D has been proposed as …

N-Acetylcysteine in Endometriosis: A Systematic Review of Biological Rationale and Clinical Evidence.

Endometriosis is a chronic inflammatory and estrogen-dependent disease in which oxidative stress, immune dysregulation, and lesion-supportive microenvironmental signaling contribute to lesion development. N-acetylcysteine (NAC), a glutathione-replenishing and redox-modulating agent, has …

The genetics of primary dysmenorrhea: a systematic review.

Dysmenorrhea is the most common gynaecological condition in women of reproductive age. Approximately 90% of cases are primary dysmenorrhea (PDM) which is not associated with underlying pathology. Dysmenorrhea can have …

Role of sRAGE in clinical heterogeneity and inflammation in endometriosis patients undergoing IVF; case-control study.

Endometriosis is a multifactorial, chronic inflammatory disorder that affects a substantial proportion of women during their reproductive years and is frequently associated with pelvic pain and infertility. Accumulating evidence suggests …

Surgical management of endometriosis: surgical techniques, adjuvant therapy, and long-term management Number 10 - 2026.

• Surgical outcomes in endometriosis vary substantially according to disease phenotype, symptom profile, and reproductive priorities. • Excisional surgery for ovarian endometriomas is associated with lower recurrence rates but carries …

Intestinal endometrosis mimicking Crohn's disease: a rare cause of nonspecific abdominal pain.

Beyond growing teratoma syndrome: post-treatment manifestations and diagnostic challenges following ovarian immature teratoma.

Growing teratoma syndrome (GTS) is a rare condition classically associated with platinum-based chemotherapy for malignant ovarian germ cell tumors. However, post-treatment findings following ovarian immature teratoma may represent a broader …

Immune-epigenetic-metabolic crosstalk: attempting to unravel the multidimensional mechanisms of immune evasion in endometriosis.

The survival of ectopic endometrial lesions in endometriosis critically depends on their ability to evade immune recognition and clearance by the host, a process known as immune evasion. Recent studies …

Endometriosis as a cause of reduced IVF success rates: guilty beyond reasonable doubt?

Endometriosis is a chronic inflammatory disease that affects around 10% of women of reproductive age and is frequently associated with infertility. Despite its high prevalence in assisted reproductive technology (ART) …

Bisphenol exposure and gynecological health: A narrative review of current evidence and knowledge gaps.

The widespread use of plastic has led to exposure to chemicals like bisphenols (BPs), particularly bisphenol A (BPA), which are crucial in the production of polycarbonate plastics and epoxy resins. …