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Safety of current strategies to manage moderate to severe pain in patients with endometriosis.

Medical therapy is crucial in the long-term management of endometriosis, and its clinical efficacy must be balanced with a favorable safety profile.

Published: Aug. 25, 2025, midnight
Factors Affecting Hormonal Therapy Ineffectiveness and Discontinuation due to Adverse Effects in Patients with Endometriosis-Associated Pain.

Endometriosis contributes to 5-21% of hospital admissions for pelvic pain. While hormonal therapies are pivotal in managing endometriosis-related pain, no single hormonal treatment suits all patients. We aimed to assess …

Published: Aug. 18, 2025, midnight
Anti-cancer Drugs in Endometriosis Management: Mechanisms and Therapeutic Potential.

Endometriosis is a widespread estrogen-driven condition causing pelvic pain and infertility in women. This disease shares five features with cancer: Intrinsic growth signals, insensitivity to antiproliferative signals, impaired apoptosis, induction …

Published: Aug. 7, 2025, midnight
Gynecologic postoperative anti-adhesion barriers: From biomaterials to barrier development.

Gynecologic postoperative adhesions (GPOA) remain an under-appreciated source of morbidity despite advances in minimally invasive surgery. Adhesions forming after myomectomy, extensive endometriosis excision, repeat caesarean section, or hysteroscopic adhesiolysis develop …

Published: Aug. 5, 2025, midnight
Gastric ectopic pancreatic ductal adenocarcinoma coexisted with endometriosis mimick advanced disease: a case report and literature review.

Ectopic pancreas (EP) is most commonly located in the upper gastrointestinal tract, particularly in the stomach. Malignant transformation of EP is exceptionally rare, and due to its very low incidence, …

Published: July 24, 2025, midnight
Characterization of key genes and immune cell infiltration associated with endometriosis through integrating bioinformatics and experimental analyses.

Endometriosis (EM) is the most common gynecological disease in women of childbearing age. This study aims to identify key genes and screen drugs that may contribute to EM treatment.

Published: March 31, 2025, midnight
A novel senotherapeutic strategy with azithromycin for preventing endometriosis progression.

Endometriosis is an estrogen-dependent chronic inflammatory disease, however the mechanisms underlying inflammation remain unclear. Non-hormonal drugs that can prevent endometriosis progression and resolve endometriotic infertility are urgently required. We thus …

Published: March 26, 2025, midnight
Prescription patterns and the cost of antihyperglycemic drugs in patients with diabetes mellitus in Iran from 2014 to 2019.

Diabetes mellitus (DM) is characterized by high blood glucose levels and abnormalities in metabolism. In 2021, 15.14% of adult Iranians had DM. The purpose of this study is to provide …

Published: March 15, 2025, midnight
Mitochondrial Involvement in the Pathogenesis of Endometriosis and its Potential as Therapeutic Targets.

Endometriosis is an estrogen-dependent benign disease characterized by the development of endometrial tissue outside the uterus. This intricate ailment markedly affects a patient's well-being and lacks a definitive cure. Endometriotic …

Published: March 10, 2025, midnight
Can Anticancer Drugs Be A Promising Candidate for The Treatment of Endometriosis?

Endometriosis, a benign gynecological disorder affecting 10-15% of women during their reproductive years, is characterized by the growth of endometrial tissue outside the uterus. Despite its prevalence, the exact pathophysiology …

Published: Feb. 23, 2025, midnight
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