Endometriosis is a chronic, estrogen-dependent inflammatory disease with heterogeneous clinical manifestations and uncertain systemic immune involvement. This study aimed to characterize peripheral immune profiles and circulating tumor markers in women …
Deep infiltrative endometriosis (DIE) is characterized by the infiltration of endometrial tissue into the pelvic organs, such as the rectovaginal septum, utero-ovarian, and uterosacral ligaments. Bowel involvement occurs in approximately …
Adenomyosis is an estrogen-dependent disease featuring chronic inflammation. This study was undertaken to investigate whether the vagal tone is reduced in patients with adenomyosis as compared with healthy women. We …
Endometriosis is a chronic, estrogen-dependent disease commonly affecting pelvic organs. Lymph node involvement is rare and even more so when leading to herniation. We report a rare case of a …
Previous studies show that orphan nuclear receptor 4A1 (NR4A1) regulated endometriotic cell growth, survival, estrogen receptor β (ERβ), mTOR signaling and fibrosis. NR4A2 is also expressed in epithelial and stromal …
The menstrual cycle induces a wide range of physiological changes in the skin and its appendages, often overlooked in dermatologic practice. Catamenial dermatoses, influenced by hormonal fluctuations, present with cyclical …
Endometriosis is an estrogen-dependent disease with unclear pathogenesis. Recent evidence suggests that ferroptosis plays an important role in the development of endometriosis. In this study, we aimed to explore whether …
Endometriosis is a chronic gynecologic disease of reproductive-age women, causing menstrual pain and infertility. Endocrine and inflammatory mechanisms drive its development, with estrogen/progesterone imbalance contributing to extrauterine implantation and persistence …
Endometriosis is a prevalent gynaecological disorder characterized by estrogen-dependent lesions. Pain-particularly dysmenorrhea, chronic pelvic pain, and dyspareunia-is the hallmark symptom of endometriosis. While pain mechanisms remain poorly understood, mast cells …
Endometriosis and uterine fibroids are estrogen-dependent gynecological disorders with an increasing burden to women's health worldwide. Despite overlapping symptoms and long-term consequences, the magnitude of their co-occurrence remains unclear.