What is the optimal timing of progesterone exposure to achieve live births for day-6 blastocysts in artificial frozen-thawed embryo transfer (FET) cycles?
Bilateral salpingo-oophorectomy (BSO) and hormone replacement therapy (HRT) exert opposing effects on systemic sex hormone exposure. Although HRT is frequently prescribed following BSO to mitigate surgical menopause, their combined impact …
Endometriosis is a prevalent gynecological disorder associated with chronic low-grade inflammation, yet diagnosis is often delayed because symptoms are non-specific and definitive confirmation typically relies on invasive procedures. Composite indices …
This study aims to investigate the effect of endometriosis (EMs) on fertility and to assess the causal relationship between EMs and fertility using two-sample Mendelian randomization (MR). We conducted an …
Phthalates (PAEs), typical endocrine-disrupting chemicals (EDCs) that accumulate in the human body to induce reproductive toxicity, have epidemiological links to endometriosis (EM), but the underlying micro-mechanisms remain unclear. Ferroptosis is …
Letrozole and other aromatase inhibitors are increasingly recognized as first-line ovulation induction (OI) medications, offering an efficient and physiologic approach to ovarian stimulation that enhances outcomes in reproductive medicine. By …
Female reproductive disorders influence women's physical and mental well-being, and the sustainability of the family. However, it is unclear whether lifestyle factors, including sedentary behaviors and physical activity, could impact …
Environmental exposures are increasingly linked to reproductive dysfunctions such as endometriosis, ovarian insufficiency, and polycystic ovary syndrome (PCOS). Through endocrine disruption, oxidative stress, and epigenetic pathways, heavy metals (such as …
Firefighter exposure to contaminants focus of new report | British Transport Police now using live facial recognition Emergency Services Times
Women with inflammatory bowel disease (IBD) experience distinct physiologic and clinical challenges across their lifespan. In childhood and adolescence, early exposure to corticosteroids, chronic inflammation, and malnutrition may impair pubertal …