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Gut Microbiota, Circulating Metabolites and Risk of Endometriosis: A Two-Step Mendelian Randomization Study.

Epidemiological studies and animal models have suggested a possible link between gut microbiota (GM), circulating metabolites, and endometriosis (EMs) pathogenesis. However, whether these associations are causal or merely due to …

Published: Dec. 13, 2024, midnight
Butyrate as a Potential Modulator in Gynecological Disease Progression.

This review investigates the therapeutic potential of butyrate, a short-chain fatty acid (SCFA) produced by gut microbiota, in the prevention and treatment of various gynecological diseases, including polycystic ovary syndrome …

Published: Dec. 4, 2024, midnight
The gut-reproductive axis: Bridging microbiota balances to reproductive health and fetal development.

The gut microbiota is a highly complex microbial community residing in the digestive tract of humans and animals, closely linked to host health. Dysbiosis within the gut microbiota has been …

Published: Nov. 22, 2024, midnight
The causality between gut microbiota and endometriosis: a bidirectional Mendelian randomization study.

Observational studies and animal experiments had suggested a potential relationship between gut microbiota abundance and pathogenesis of endometriosis (EMs), but the relevance of this relationship remains to be clarified.

Published: Nov. 22, 2024, midnight
Causal Link between Gut Microbiota and Infertility: A Two-sample Bidirectional Mendelian Randomization Study.

To investigate the associations of the gut microbiota with reproductive system diseases, including female infertility, male infertility, polycystic ovary syndrome (PCOS), primary ovarian failure, endometriosis, uterine fibroids, uterine polyps, sexual …

Published: Nov. 18, 2024, midnight
Microbial harmony in female reproductive health: exploring the impact of intestinal flora on ovarian function and disease pathogenesis.

The intestinal microbiota is vast in type and quantity and it plays a critical role in regulating various physiological functions in the host, including intestinal function, immune response and energy …

Published: Nov. 15, 2024, midnight
The potential role of gut microbiota in the occurrence and development of endometriosis.

Endometriosis (EMT) has a significant impact on women's physical and mental health. In this study, high-throughput sequencing technology was employed to detect differences in gut microbiota between EMT patients and …

Published: Oct. 31, 2024, midnight
The role of gut and genital microbiota and the estrobolome in endometriosis, infertility and chronic pelvic pain.

Endometriosis is a chronic, burdensome condition that is historically understudied. Consequently, there is a lack of understanding of the etiology of the disease and its associated symptoms, including infertility and …

Published: Oct. 14, 2024, 1:20 p.m.
The gut microbiota: emerging biomarkers and potential treatments for infertility-related diseases.

Infertility is a disease of impaired fertility. With socioeconomic development, changes in human lifestyles, and increased environmental pollution, the problem of low human fertility has become increasingly prominent. The incidence …

Published: Sept. 26, 2024, midnight
High-fat diets promote peritoneal inflammation and augment endometriosis-associated abdominal hyperalgesia.

Immune dysfunction is one of the central components in the development and progression of endometriosis by establishing a chronic inflammatory environment. Western-style high-fat diets (HFD) have been linked to greater …

Published: Nov. 13, 2023, midnight
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