Latest Articles

Reduced type 2 epithelial-mesenchymal transition serves as a risk factor for the progression from endometriosis to endometriosis-associated ovarian cancer.

Endometriosis-associated ovarian cancer (EAOC) is a rare subtype of ovarian cancer arising from the malignant transformation of endometriosis (EMS). Despite growing clinical awareness, its underlying pathogenic mechanisms are not fully …

Symptom Burden in Adenomyosis: A Comparative Analysis With Peritoneal and Deep Infiltrating Endometriosis.

Adenomyosis frequently coexists with endometriosis and shares overlapping symptoms; however, the symptom burden of isolated adenomyosis remains insufficiently defined. The aim of this study was to compare the severity and …

miR-769-5p inhibits cellular behaviors associated with endometriosis progression by directly targeting follistatin in vitro.

The pathogenesis of endometriosis (EM) remains intricate and multifactorial. This study aimed to investigate the biological functions of microRNA-769-5p (miR-769-5p) in an in vitro model of EM. Serum was obtained …

The characterization of patients with premature ovarian failure, endometriosis, and polycystic ovary syndrome in women attending comprehensive health centers in Urmia, Iran.

Research progress and future directions in circadian rhythms for uterine‑related diseases (Review).

Circadian rhythms are ~24 h endogenous rhythms driven by both central and peripheral clocks, with their core mechanism being a transcription‑translation feedback loop mediated by master clock genes. The present …

Bioinformatics analysis implicates ferroptosis and key hub genes in the pathogenesis of endometriosis.

Endometriosis (EMs) is a chronic gynaecological condition characterised by the ectopic growth of endometrial tissue; however, its molecular mechanisms remain insufficiently understood. Ferroptosis, an iron-dependent form of regulated cell death, …

Laparoscopically guided transversus abdominis plane block versus local wound infiltration analgesia in laparoscopic surgery for peritoneal endometriosis: A prospective randomized controlled double-blinded LTAP-trial.

Endometriosis patients often suffer from more severe pain in association with surgical procedures. The aim of this study was to investigate whether laparoscopically guided transversus abdominis plane block (LTAP) offers …

Surgical management of catamenial pneumothorax: a systematic review.

Catamenial pneumothorax is a rare manifestation of thoracic endometriosis syndrome and is associated with a high risk of recurrence despite surgical intervention. Increasingly, multimodal strategies combining thoracic surgery with adjunctive …

Endometriosis in Adolescents: A Literature Review.

Endometriosis is a chronic gynecological disorder that affects approximately 10% of women of reproductive age. In adolescents, it frequently remains underdiagnosed due to the heterogeneity of its clinical presentation. Pelvic …

Bridging the Gap Between Artificial Intelligence and Clinical Readiness in Endometriosis Diagnosis: A Systematic Review.

To systematically evaluate the methodological quality and diagnostic performance of artificial intelligence (AI) applications, specifically machine learning (ML) and deep learning (DL), in the diagnosis of endometriosis through imaging and …