Endometriosis, a chronic inflammatory disease affecting 10-15% of women of reproductive age, remains a leading cause of female subfertility. While current management strategies focus on surgical excision and hormonal suppression, …
Endometriosis is a common gynecological disorder characterized by the ectopic growth of endometrium-like tissue outside the uterine cavity and is associated with pelvic pain, infertility, and reduced quality of life. …
Endometriosis is a debilitating chronic inflammatory disorder driven by extensive molecular reprogramming. Despite significant bench research into its pathogenesis, translating these molecular discoveries into clinical practices that improve patient outcomes …
Spontaneous ovarian endometrioma rupture typically presents with acute abdominal pain, a condition often complicated by tissue edema and pelvic adhesions that increase surgical difficulty. This study aims to evaluate the …
Endometriosis is an estrogen-dependent benign inflammatory disorder characterized by the implantation of active endometrial tissue (glands or stroma) outside the uterus, with pelvic adhesions as a core hallmark. Omental endometriosis …
Three-dimensional (3D) endothelium-stromal co-cultures were established using human endometrial cells from biopsy of healthy women (n = 13) and serum samples from both healthy and endometriotic women (n = 5). …
This review aims to evaluate the potential of endometriosis models, especially patient-derived iPSC models, to gain deeper insights into the disease, thereby advancing our understanding and treatment of endometriosis. This …
The genitourinary system undergoes a complex development, making it prone to congenital anomalies. Müllerian duct anomalies are among these, affecting the uterus, cervix, and vagina due to errors in ductal …
White adipose tissue is now recognized as an active endocrine organ that secretes numerous bioactive molecules known as adipokines. These proteins regulate essential physiological processes, including energy metabolism, inflammation, and …
Primary umbilical endometriosis (Villar's nodule) is a rare entity, representing 0.5%-1% of all endometriosis cases. We report a 37-year-old multiparous woman presenting with a 7-day history of umbilical pain, swelling, …