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Long-term risk of endometrial cancer after assisted reproductive technology.

What is the risk of endometrial cancer after long-term follow-up in women treated with ART between 1983 and 2001 compared with women in the general population and subfertile women who …

Published: Feb. 7, 2025, midnight
Potential biomarkers and immune infiltration linking endometriosis with recurrent pregnancy loss based on bioinformatics and machine learning.

Endometriosis (EMs) is a chronic inflammatory disease characterized by the presence of endometrial tissue in the non-uterine cavity, resulting in dysmenorrhea, pelvic pain, and infertility. Epidemiologic data have suggested the …

Published: Feb. 3, 2025, midnight
Mapping Human Uterine Disorders Through Single-Cell Transcriptomics.

Disruptions in uterine tissue function contribute to disorders such as endometriosis, adenomyosis, endometrial cancer, and fibroids, which all significantly impact health and fertility. Advances in transcriptomics, particularly single-cell RNA sequencing, …

Published: Jan. 21, 2025, midnight
Evaluating the association between lipidome and female reproductive diseases through comprehensive Mendelian randomization analyses.

This study aimed to assess the causal relationship between lipidome and female reproductive diseases (FRDs) using an advanced series of Mendelian randomization (MR) methods. This study utilized genome-wide association study …

Published: Jan. 19, 2025, midnight
Novel screening approach for stem cell selective inhibitors and their possible translational therapeutic potential for endometriosis.

Endometriosis is an estrogen-dependent benign disease characterized by growth of the endometrial tissue outside the uterine wall. Several reports suggest the possibility of the pathogenesis and recurrence of endometriosis being …

Published: Jan. 11, 2025, midnight
Knowledge of the Benefits and Risks of Oral Contraceptive Use Among Women of Reproductive Age in Western Saudi Arabia: A Descriptive Cross-Sectional Study.

For women of reproductive age, oral contraceptives (OCs) are a well-liked and practical way to control pregnancy. OCs are also used to treat acne, irregular uterine bleeding, and premenstrual syndrome. …

Published: Dec. 26, 2024, midnight
A bioinformatics analysis of gene expression in endometrial cancer, endometriosis and obesity.

Endometrial cancer (EC), endometriosis (ENDO), and obesity (OBY) are interconnected conditions in women that may share underlying genetic pathways. This study aimed to identify shared genetic pathways and differential gene …

Published: Dec. 9, 2024, midnight
Butyrate as a Potential Modulator in Gynecological Disease Progression.

This review investigates the therapeutic potential of butyrate, a short-chain fatty acid (SCFA) produced by gut microbiota, in the prevention and treatment of various gynecological diseases, including polycystic ovary syndrome …

Published: Dec. 4, 2024, midnight
Biotechnological progresses in modelling the human endometrium: the evolution of current in vitro techniques and emerging trends.

The endometrium plays a fundamental role in the reproductive system yet many etiologies of infertility-related endometrial diseases such as endometriosis, adenomyosis, Asherman's syndrome or endometrial cancer remain unknown. There are …

Published: Dec. 3, 2024, midnight
Identification of key genes associated with endometriosis and endometrial cancer by bioinformatics analysis.

Endometriosis (EMS) is acknowledged as a risk factor for the development of endometrial cancer (EC), although the precise molecular mechanisms that underpin this association have yet to be fully elucidated. …

Published: Nov. 22, 2024, midnight
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