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Targeting endometrial stem cell in endometriosis treatment, a scoping review.

Endometriosis is characterized by the ectopic implantation of endometrial tissue affecting reproductive-aged women. Available therapies have still unmet needs namely due to recurrence rates and systemic side effects. Emerging evidence …

Published: Jan. 20, 2026, midnight
Mucin Biology as a Local Diagnostic and Promising Therapeutic Target in Endometriosis: Expression and Glycosylation Profiling.

Endometriosis (EM) is a chronic inflammatory disease characterized by the growth of endometrial-like tissue outside the uterus, yet its molecular mechanisms remain poorly understood. This study investigated the expression of …

Published: Jan. 20, 2026, midnight
The evolution of endometriosis research models: a paradigm shift from immortalized cell lines to organoids†.

Endometriosis is a complex condition affecting 10% of reproductive-age women worldwide, yet its study has long been hindered by the shortcomings of traditional research models. This review aims to propose …

Published: Jan. 19, 2026, midnight
Validation of the deep pelvis endometriosis index (dPEI) to evaluate surgical outcomes of robotic-assisted surgery for endometriosis.

The Deep Pelvic Endometriosis Index (dPEI) is a preoperative MRI-based score initially validated to predict surgical outcomes in patients undergoing laparoscopic treatment for deep pelvic endometriosis (DPE). Its applicability in …

Published: Jan. 19, 2026, midnight
The iron-ferroptosis axis in bone homeostasis: a potential complementary pathway for osteoporosis in endometriosis.

Endometriosis, a chronic gynecological disorder, is clinically associated with an increased risk of osteoporosis. While this link has been primarily attributed to hypoestrogenism resulting from the disease process or its …

Published: Jan. 19, 2026, midnight
Characteristics and Preoperative Management of Adolescent Patients With Pathology-Confirmed Endometriosis: A Multi-Institutional Study.

Endometriosis affects an estimated 25% to 75% of adolescent patients with chronic pelvic pain; the diagnosis is made surgically and treatment typically consists of hormone suppression and pain management strategies. …

Published: Jan. 19, 2026, midnight
Immunohistochemical Detection of the Mechano-Gated Piezo Channels in the Normal Endometrium and in Endometriosis.

Endometriosis is an inflammatory estrogen-dependent disorder characterized by pain, dyspareunia, dysmenorrhea, and infertility. This is due to the invasion of different organs by endometrial tissue that causes inflammation, angiogenesis, and …

Published: Jan. 19, 2026, midnight
Opioid-sparing by low-dose ketamine for endometriosis surgery. A single-center, prospective, randomized, trial.

Endometriosis affects 10% of women of childbearing age and 25-50% of infertile women worldwide. Although most patients with endometriosis are completely asymptomatic, there is still a significant proportion of patients, …

Published: Jan. 18, 2026, midnight
Unraveling the VEGF-ETS1 axis: a transcriptomic and single-cell analysis of angiogenesis in endometriosis.

Endometriosis (EM) is a chronic inflammatory gynecological disorder characterized by ectopic endometrial-like lesions, where aberrant angiogenesis is a hallmark driving lesion establishment and progression. However, the transcriptional mechanisms underlying pathological …

Published: Jan. 16, 2026, midnight
Network Pharmacology and Multi-omics Investigation of Yiqi Huoxue Formula's Molecular Mechanisms in Treating Endometriosis.

Endometriosis (EMs), a prevalent disorder characterized by pelvic pain and infertility, affects numerous bodily systems and markedly diminishes life quality. Yiqi Huoxue formula (YQHXF) has demonstrated promising therapeutic efficacy. However, …

Published: Jan. 16, 2026, midnight
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