Systemic isotretinoin remains the most effective therapy for severe acne and is increasingly prescribed off-label for milder disease and other sebaceous disorders such as rosacea, seborrhea, folliculitis decalvans, and hidradenitis …
Endometriosis is a highly prevalent, chronic gynecological disorder characterized by the ectopic presence of endometrial-like tissue, driving significant morbidity and chronic pelvic pain. Pathologically, it is increasingly recognized as a …
Endometriosis (EM), a disorder driven by persistent systemic inflammation, impacts around 10% of women in their reproductive period, often diagnosed only via surgery. Metabolic alterations, particularly in lipid metabolism, may …
Ferroptosis is a potential target for the treatment of endometriosis (EMs). The role of andrographolide (AP) in the ferroptosis has gradually attracted attention, but its mechanism of action in endometriosis …
Endometriosis has been linked to cardiometabolic alterations, but whether these associations vary by disease severity or phenotype is unclear. We examined lipid profiles across endometriosis diagnosis, stage, and typology.
Gynecological endocrine disorders, including polycystic ovary syndrome (PCOS), endometriosis as well as primary ovarian insufficiency (POI)/premature ovarian failure (POF), significantly impact women's reproductive health and overall well-being. While these conditions …
Menstrual blood (MB), once thought of as nothing more than biological waste, has now come to be regarded as a noninvasive and low-cost diagnostic tool with great potential for women's …
Iron is an essential micronutrient element for human. It participates in energy metabolism, enzyme activation, immune system and other metabolic functions. In this review, the potential role of iron in …
Endometriosis (EM) is a chronic inflammatory disorder characterized by the growth of ectopic endometrial-like tissue and fibrosis. Metabolic reprogramming, particularly enhanced glycolysis, and immune microenvironment dysregulation are key features of …
The ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol (NHHR), a new lipid marker, can comprehensively reflect the lipid metabolic status of an individual. This study aimed to investigate …