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Inhibition of lysine-specific histone demethylase 1A suppresses adenomyosis through reduction in ectopic endometrial stromal cell proliferation, migration, and invasion.

Deep endometriosis is now referred to as adenomyosis externa, whereas adenomyosis is once known as endometriosis interna. Lysine-specific histone demethylase 1A (KDM1A, commonly LSD1) is a lysine demethylase that targets …

Published: Nov. 22, 2024, midnight
Association between chronic stress-related amygdala metabolic activity and lymph node metastasis in endometrial cancer - Nature.com

Association between chronic stress-related amygdala metabolic activity and lymph node metastasis in endometrial cancer Nature.com

Published: Nov. 18, 2024, 6:27 a.m.
Autophagy Involvement in Non-Neoplastic and Neoplastic Endometrial Pathology: The State of the Art with a Focus on Carcinoma.

Autophagy is a cellular process crucial for maintaining homeostasis by degrading damaged proteins and organelles. It is stimulated in response to stress, recycling nutrients and generating energy for cell survival. …

Published: Nov. 12, 2024, midnight
Model Predicts Lymph Node Metastasis in EC - Physician's Weekly

Model Predicts Lymph Node Metastasis in EC Physician's Weekly

Published: Nov. 4, 2024, 7:55 p.m.
Loss of vimentin expression in preoperative biopsies independently predicts poor prognosis, lymph node metastasis and recurrence in endometrial cancer - Nature.com

Loss of vimentin expression in preoperative biopsies independently predicts poor prognosis, lymph node metastasis and recurrence in endometrial cancer Nature.com

Published: Oct. 19, 2024, 12:50 a.m.
Clear Cell Carcinoma Arising From Adenomyotic Cyst: A Case Report.

Clear cell carcinoma often arises from endometriosis, primarily from ovarian chocolate cysts and much less frequently from adenomyosis. We herein report a case of clear cell carcinoma arising from adenomyotic …

Published: Oct. 14, 2024, midnight
Advances in research on malignant transformation of endometriosis-associated ovarian cancer.

Endometriosis (EMs) is a prevalent chronic gynecological condition that depends on estrogen, marked by the presence of active endometrial tissue (glands and stroma) outside the uterus. Although pathologically benign, it …

Published: Oct. 9, 2024, midnight
PAK5-mediated PKM2 phosphorylation is critical for anaerobic glycolysis in endometriosis.

P21-activated kinase 5 (PAK5) belongs to the PAK-II subfamily, which is an important regulator of cell survival, adhesion, and motility. However, the functions of PAK5 in endometriosis remain unclear. Here, …

Published: Sept. 27, 2024, midnight
Melatonin: Current evidence on protective and therapeutic roles in gynecological diseases.

Melatonin, a potent antioxidant and free radical scavenger, has been demonstrated to be effective in gynecological conditions and female reproductive cancers. This review consolidates the accumulating evidence on melatonin's multifaceted …

Published: March 11, 2024, midnight
Management of a Nulliparous IVF Patient with a Declined Ovarian Reserve After Discovery of an Atypical Ovarian Endometriotic Cyst.

Endometriosis (EM) is a common cause of infertility, and an ovarian endometriotic cyst may affect the ovarian reserve, ovulation, and endometrial receptivity. The majority of EM cases are benign; however, …

Published: Oct. 2, 2023, midnight
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