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The interplay of microbiome, molecular mechanisms, and fertility -an integrated review.

The human microbiome, particularly the gut and reproductive tract microbiota, plays a critical role in regulating fertility through complex molecular and immunological mechanisms. This review synthesizes emerging evidence on the …

Published: Dec. 26, 2025, midnight
Systematic analyses uncover endocrine-disrupting chemical-responsive genes linked to endometriosis.

Endometriosis is a chronic, estrogen-dependent disorder influenced by both genetic and environmental factors, including endocrine-disrupting chemicals (EDCs). This study aimed to identify EDC-responsive genes contributing to endometriosis risk by integrating …

Published: Dec. 22, 2025, midnight
Andrographolide blocked the progression of endometriosis by promoting ferroptosis via inhibiting anabolism of serine.

Ferroptosis is a potential target for the treatment of endometriosis (EMs). The role of andrographolide (AP) in the ferroptosis has gradually attracted attention, but its mechanism of action in endometriosis …

Published: Dec. 18, 2025, midnight
Development of an AI-based magnetic resonance imaging reading support program (AMP) for deep endometriosis diagnosis.

Diagnosis of endometriosis faces significant challenges including diagnostic delay and reliance on invasive procedures. Deep endometriosis (DE) poses additional difficulties in non-invasive diagnosis due to its subtle and complex imaging …

Published: Dec. 8, 2025, midnight
Expanding the genetic landscape of endometriosis: Integrative -omics analyses implicate key genes and pathways in a multi-ancestry study of over one million women.

We report the findings of a genome-wide association study (GWAS) meta-analysis of endometriosis across 14 biobanks worldwide, including 32% non-European patient participants, as part of ​the ​Global Biobank Meta-Analys​i​s Initiative​ …

Published: Dec. 4, 2025, midnight
Endometrial Stromal Cells from Endometriosis Patients Reflect Lesion-Type-Specific Heterogeneity.

Endometriosis, a disease affecting about one out of ten women, is characterized by the growth of endometrial-like tissue outside the uterine cavity. There is significant disease heterogeneity, but the pathophysiological …

Published: Nov. 28, 2025, midnight
Proteomics International Secures Grant for Endometriosis Diagnostic Test - MSN

Proteomics International Secures Grant for Endometriosis Diagnostic Test MSN

Published: Nov. 25, 2025, 2:30 p.m.
Single-cell and spatially resolved omics reveal transcriptional and metabolic signatures of ovarian endometriomas.

Endometriosis involves ectopic growth of endometrial-like tissue, yet the spatial transcriptomic and metabolic landscape of ovarian endometriomas remains poorly understood. This investigation presents a comprehensive multi-omics analysis of ovarian endometriomas …

Published: Nov. 22, 2025, midnight
Metabolomics reveals the therapeutic efficacy of liposomal resvida in endometrial cancer through regulating autophagy-related gene expression - springermedicine.com

Metabolomics reveals the therapeutic efficacy of liposomal resvida in endometrial cancer through regulating autophagy-related gene expression springermedicine.com

Published: Nov. 21, 2025, 2:26 a.m.
THBS1 identificated as an endometriosis biomarker through evidence from single-cell and bulk transcriptomic profiling.

Endometriosis affects a substantial number of women of reproductive age, yet current diagnostic methods rely on invasive procedures. To address this limitation, we investigated THBS1 as a potential biomarker and …

Published: Nov. 21, 2025, midnight
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