The efficacy of ultrasound-guided treatment of ovarian endometriosis cysts: A meta-analysis.
The purpose of this meta-analysis was to systematically assess the efficacy of ultrasound-guided therapy of ovarian endometriosis cyst (OEC). Several databases were searched to gather published studies on the efficacy …
From Endometriosis to Endometriosis-Associated Ovarian Cancer: Molecular Mechanisms, Risk Stratification and Clinical Implications.
Endometriosis is a chronic estrogen-dependent disorder affecting approximately 10% of women of reproductive age. Increasing epidemiological and molecular evidence indicates that it may represent a precursor condition for a subset …
Is colorectal resection necessary to improve pain and fertility outcomes in patients with deep endometriosis?
Bowel endometriosis is often considered an indication for extensive surgical management, including colorectal resection, in women undergoing surgery for concomitant endometriosis at other sites. However, several contemporary studies show little …
Three-Dimensional Architecture of Ectopic Epithelium and Vasculature in Ovarian Endometriosis Revealed by Tissue-Clearing Imaging.
Ovarian endometriosis (OEM) is characterised by ectopic endometrial tissue growth within the ovary. In these ectopic lesions, the ectopic epithelium plays a crucial role in OEM progression and has been …
Beyond nociception: rethinking pain in ovarian endometriosis a pilot study.
Endometriosis affects 1 in 10 women, is the most common cause of chronic pelvic pain, classically known for its nociceptive pain mechanisms. Medical therapies have limited efficacy, prevent pregnancy, and …
Effects of E2/ERβ on follicular granulosa cells and on AMH/Smad signalling in endometriosis.
Patients with endometriosis have greater risk of infertility, which is associated with compromised ovarian function. Dysfunction in follicular granulosa cells and hyperactivation of oestrogen receptor beta (ERβ) are evident in …
TMEM119 Links to Ovarian Endometriosis Progression via MAPK-Mediated Suppression of Ectopic Endometrial Stromal Cell Senescence.
Transmembrane protein TMEM119 has been implicated in tumor progression (e.g., ovarian cancer), but its role and underlying mechanism in ovarian endometriosis (EM) remain elusive. Thus, this study aimed to investigate …