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Unveiling Potential Blood Markers for Endometriosis Through the Integration and Experimental Validation of Immune Cell Traits Genome and Genome-Wide Associated Data.

While endometriosis (EM) has been previously associated with multiple immune factors, the causal relationship underlying these associations remains unclear.

Published: March 19, 2025, midnight
Nanomicelle curcumin improves oxidative stress, inflammatory markers, and assisted reproductive techniques outcomes in endometriosis cases: a randomized clinical trial.

We studied the effect nanomicelle curcumin on oxidative stress markers, pro-inflammatory cytokines, and assisted reproductive techniques (ART) outcomes in endometriosis cases. This randomized controlled trial was conducted on 50 women …

Published: March 15, 2025, midnight
Causal Relationship Between Abortion and Endometriosis: A Bidirectional Two-Sample Mendelian Randomization Study.

The relationship between abortion and endometriosis (EMS) has been inconsistent in previous observational studies and remains controversial. We intended to examine the causal relationship between abortion and EMS.

Published: March 4, 2025, 12:04 a.m.
Causal Effect Between Natural Hair Color and Endometriosis in a European Population: A Two-Sample Mendelian Randomization.

Previous observational studies have suggested an association between natural hair color and the risk of endometriosis; however, the causal relationship remains unclear. Here, we conducted a two-sample Mendelian randomization (MR) …

Published: Feb. 25, 2025, midnight
Prioritization of potential drug targets in ovarian-related diseases: Mendelian randomization and colocalization analyses.

To identify key genes and potential drug targets for ovarian-related diseases through genome-wide Mendelian randomization (MR) and colocalization analyses.

Published: Feb. 21, 2025, midnight
Identification of potential diagnostic biomarkers and drug targets for endometriosis from a genetic perspective: a mendelian randomization study.

Endometriosis (EM) is a chronic disease severely impacting reproductive health, with its exact cause still unclear. In-depth understanding of the etiology and pathogenesis of EM from the perspective of genetics …

Published: Feb. 20, 2025, midnight
Association of Sleep Traits, Physical Activity, and Sedentary Leisure Behavior With Female Reproductive Health: A Two-Sample Mendelian Randomization Analysis.

Living habits affect female endocrine function and fertility, along with aging and other life factors. Because of this, female reproductive health can be promoted through living habit adjustment.

Published: Feb. 20, 2025, midnight
Insomnia and Female Reproductive Diseases: A Cross-Sectional and Mendelian Randomization Study.

Insomnia is increasingly emerging as a significant concern in public health, with a longstanding emphasis on its relationship with overall well-being. Nevertheless, few research has been devoted to investigating the …

Published: Feb. 18, 2025, midnight
Causal Links Between Brain Functional Networks and Endometriosis: A Large-Scale Genetic-Driven Observational Study.

Endometriosis is a chronic gynecological disorder that significantly impacts women of reproductive age. Recent evidence suggests a bidirectional link between endometriosis and brain functional networks, though the causal mechanisms remain …

Published: Feb. 11, 2025, midnight
Identification of potential druggable targets for endometriosis through Mendelian randomization analysis.

Endometriosis (EM) is a widely recognized disorder in gynecological endocrinology. Although hormonal therapies are frequently employed for EM, their side effects and outcome limitations underscore the need to explore the …

Published: Jan. 22, 2025, midnight
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