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Impact of the lipid-inflammation axis on endometriosis risk: a multicenter case-control study using mediation analysis.

Endometriosis (EM) is often accompanied by dyslipidemia, but the causal relationship between dyslipidemia and inflammation remains unclear. This study aimed to explore the association between the lipid-inflammation axis and EM …

Published: Nov. 13, 2025, midnight
Role of HLA-DRA-CREB3L4 regulatory axis in the pathogenesis of ovarian endometriosis: Inhibition of CREB3L4 expression by HLA-DRA increases the risk of disease.

Ovarian endometriosis is a common gynecological condition characterized by the abnormal growth of endometrial-like tissue in locations outside the uterus, and its development remains poorly understood. This study aims to …

Published: Nov. 11, 2025, midnight
Association between serum carotenoids and risk of endometriosis evidence from NHANES data.

Endometriosis is a prevalent gynecological disorder, with its pathogenesis potentially linked to oxidative stress. Carotenoids, as natural antioxidants, may play a role in its prevention. This study aimed to investigate …

Published: Nov. 10, 2025, midnight
Machine-learning-derived prediction models of recurrence of ovarian endometriosis after laparoscopic surgery.

Endometriosis is a long-term health problem that affects a significant number of women globally. Among the various forms of endometriosis, ovarian endometriosis (OEM) is the most prevalent. This research aimed …

Published: Nov. 10, 2025, midnight
Causal associations between sleep disorders and endometriosis: A Mendelian randomization analysis.

Evidence have indicated a correlation between sleep disorders and endometriosis, but the causal relationship remains uncertain. This study utilized Mendelian randomization (MR) approach to investigate the causal associations between sleep …

Published: Nov. 10, 2025, midnight
Analysis of related factors for postoperative recurrence of abdominal wall endometriosis: a retrospective cohort study.

Published: Nov. 10, 2025, midnight
Analysis of Risk Factors Associated With Persistent Noncyclic Pelvic Pain Despite Hormonal Treatment in Patients With Endometriosis.

To identify risk factors that predict the persistence of noncyclical pelvic pain in patients with endometriosis despite receiving hormone therapy.

Published: Nov. 9, 2025, midnight
Nanodrug impact on female reproductive health and fetal development: From translation approaches to long-term safety concern.

Biomaterials for drug delivery offer significant advantages over conventional medications, including enhanced cellular uptake, improved drug stability, targeted delivery, and controlled drug release. Cutting-edge nanodrugs delivery approaches such as drugs …

Published: Nov. 5, 2025, midnight
Altered Apoptosis in Endometriosis Compared with Ovarian Carcinoma.

Background and Objectives: Endometriosis has been shown to be associated with an increased cancer risk, and apoptosis may be important in the pathophysiology of endometriosis. To date, it remains unclear …

Published: Nov. 5, 2025, midnight
TET3-overexpressing macrophages are a unifying pathogenic feature with therapeutic potential in chronic inflammatory diseases.

Increased activation of the NLRP3 inflammasome in immune cells, including macrophages, has been implicated in the pathogenesis of multiple chronic inflammatory diseases. Targeted depletion of macrophages has been explored as …

Published: Nov. 3, 2025, midnight
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