HOXB13 in cancer development: molecular mechanisms and clinical implications EurekAlert!
Endometriosis (EMS) is a prevalent estrogen-dependent gynecological disorder characterized by ectopic growth of endometrial tissue. Central to its pathophysiology, peritoneal CD14hi macrophages exhibit a pro-EMS phenotype and drive disease progression. …
Ovarian clear cell carcinoma (OCCC) represents a rare and aggressive subtype of epithelial ovarian cancer with distinctive clinical and molecular characteristics. However, the identification, origin, and molecular features of the …
Pingchong Jiangni recipe (PJR) is a Chinese herbal formula that has been used clinically for decades in the treatment of endometriosis, with effects such as shrinking the lesions and reducing …
Endometrial regeneration is a cornerstone of reproductive health, with the extracellular matrix (ECM) playing a pivotal role in tissue repair, regeneration, and fertility restoration. Dysregulated ECM remodeling is at the …
Endometriosis is a disease characterized by the presence of endometrial glands and stroma outside of the uterine corpus, often clinically presenting with pain and/or infertility. Ectopic lesions exhibit features characteristic …
Figure 3. Mechanisms of action of related EMT and MMPs in EMS, OC, BC,... researchgate.net
The fibrosis mechanism in endometriosis is not elucidated. We investigated the role of eosinophil in fibrosis of endometriosis. The endometriotic stromal cells (ESCs) and endometrial epithelial cells (EECs) were subjected …
Endometriosis is a prevalent, complex, inflammatory condition associated with a diverse range of symptoms and comorbidities. Despite its substantial burden on patients, population-level studies that explore its comorbid patterns and …
Endometriosis-the growth of uterine-like tissue outside the uterus-is a devastating disease that severely reduces the quality of life of those affected, resulting in missed days from school and work due …