Latest Articles

Immune dysregulation in endometriosis: the T cell perspective.

Endometriosis is a chronic inflammatory, hormone dependent disorder that affects more than 200 million women worldwide. Immune dysfunction has emerged as one of the predominant mechanisms facilitating endometriosis lesion growth …

Endometrial organoids to model benign disorders affecting the endometrium.

The endometrium is a highly dynamic and complex tissue lining the uterus, playing a central role in reproductive health. Despite its importance, the pathogenesis of many benign endometrial disorders remains …

A preliminary single-cell map of endometriosis suggests roles for fibroblast metabolism and macrophage polarization in disease progression.

Surgical management of ovarian endometrioma in a patient with fibrodysplasia ossificans progressiva: a case report.

Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare (prevalence ~ 1:2 million), devastating genetic disorder characterized by progressive heterotopic ossification. Crucially, surgical trauma is a potent trigger for catastrophic new bone …

[Angelica sinensis polysaccharide ameliorates endometriosis in rats by restoring autophagic homeostasis via inhibition of Keap1/Nrf2/HO-1-mediated oxidative stress].

To investigate whether Angelica sinensis polysaccharide (ASP) ameliorates endometriosis (EMT) by suppressing oxidative stress and restoring autophagy via the Kelch-like ECH-associated protein 1 (Keap1)/nuclear factor erythroid 2-related factor 2 (Nrf2)/heme …

Intestinal Endometriosis Mimicking Ulcerative Colitis-Associated Neoplasia: A Case Report.

Intestinal endometriosis is a benign condition characterized by the presence of endometrial tissue within the bowel wall, often mimicking colorectal malignancy. Its coexistence with ulcerative colitis (UC) is rare and …

Harnessing mangroves for epigenetic therapies.

Mangroves are valuable reservoirs of diverse phytochemicals with significant therapeutic potential. Beyond their ecological roles, these bioactive compounds can influence epigenetic mechanisms, heritable changes in gene expression without alterations in …

Hypoxia-induced miR-21-5p promotes autophagy by downregulating CDC25A in endometriosis.

Endometriosis is a common gynecological disorder affecting women of reproductive age, often leading to chronic pain, reduced quality of life, and infertility. It is characterized by ectopic endometrial growth within …

Differences in epigenetic age acceleration according to a diagnosis of endometriosis/adenomyosis: the Norwegian Mother, Father and Child Cohort Study.

Women with endometriosis and adenomyosis have an increased risk of age-dependent diseases such as cardiovascular disease and cancer. Whether this reflects differences in biological age is unknown.

Nanoceria as an Innovative Therapy for Endometriosis: Impact on Lesion Reduction and Therapeutic Optimization.

Endometriosis is a chronic inflammatory disease with limited therapeutic options and frequent adverse effects. This study aimed to develop and evaluate cerium oxide nanoparticles (nanoceria) as a potential therapeutic strategy …