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Histone lactylation: a novel epigenetic bridge linking cellular metabolism to benign and malignant gynecological diseases.

Lactic acid modification of histones represents an emerging post-translational modification that establishes a critical link between cellular metabolic reprogramming and epigenetic regulation through the covalent binding of lactic acid to …

Published: June 23, 2026, midnight
E-cigarette use (vaping) and cigarette smoking are associated with reduced markers of ovarian reserve: a cross-sectional study of 16,087 women.

E-cigarette use (vaping) is rapidly increasing among women of reproductive age, with an estimated one in five women aged 15-45 now using e-cigarettes in England. Despite being promoted as a …

Published: June 23, 2026, midnight
Correction: Clinical characteristics of endometriosis with and without dysmenorrhea diagnosed by laparoscopy.

[This corrects the article DOI: 10.3389/fmed.2025.1635960.].

Published: June 23, 2026, midnight
Pharmacovigilance profiles of three generations of mineralocorticoid receptor antagonists and network toxicology analysis.

Mineralocorticoid receptor antagonists, spironolactone, eplerenone, and finerenone, are cornerstone therapies in cardiovascular and renal diseases. While their efficacy is established, a systematic, head-to-head comparison of their post-marketing safety profiles based …

Published: June 23, 2026, midnight
Three-Dimensional Organoid-like Co-Culture of Human Endometrial Endothelial and Stromal Cells to Study Endometriosis-Associated Responses.

Three-dimensional (3D) endothelium-stromal co-cultures were established using human endometrial cells from biopsy of healthy women (n = 13) and serum samples from both healthy and endometriotic women (n = 5). …

Published: June 23, 2026, midnight
Cutting through the pain: The role of the registered nurse first assistant in endometriosis surgery.

Multidisciplinary care for endometriosis often includes surgical diagnosis and management, and within this context, the registered nurse first assistant (RNFA) plays a critical leadership role across the perioperative continuum. Surgical …

Published: June 22, 2026, midnight
From Hope to Infection: Tubo-Ovarian Abscess After Frozen Embryo Transfer-A Case Report and Review of the Literature.

Tubo-ovarian abscess is a rare but serious complication of assisted reproductive technologies, typically following oocyte retrieval. We report a case of a 41-year-old woman with endometriosis who developed a tubo-ovarian …

Published: June 22, 2026, midnight
The Clinical Impact of Patient Embarrassment in Gynecology: A Comprehensive Review of Barriers, Consequences, and Mitigation Strategies.

Patient embarrassment represents a significant yet often underrecognized barrier to effective gynecological care. This review integrates multidisciplinary evidence from Embase, PubMed, PsycINFO, and the Cochrane Library (2000-2025) to examine the …

Published: June 22, 2026, midnight
Building Disease Models for Endometriosis: iPSCs as Game-Changers.

This review aims to evaluate the potential of endometriosis models, especially patient-derived iPSC models, to gain deeper insights into the disease, thereby advancing our understanding and treatment of endometriosis. This …

Published: June 22, 2026, midnight
Multimorbidity in Chronic Overlapping Pain Conditions: From Burden to Integrated Care.

Chronic overlapping pain conditions (COPCs) refer to a set of chronic pain disorders that frequently co-occur and may involve partially overlapping mechanisms. The U.S. National Institutes of Health currently recognizes …

Published: June 22, 2026, midnight
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