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Uterine-derived exosomes induce the M2 polarization of macrophages via miR-210-3p/ATP5D to promote endometriosis progression.

Endometriosis development is associated with peritoneal immune microenvironment abnormality; however, the specific mechanism is uncertain. We aimed to investigate the effects and underlying mechanisms of uterine cavity-derived exosomes on macrophage …

Published: Jan. 9, 2025, midnight
Optimizations of Placenta Extracellular Matrix-Loaded Silk Fibroin/Alginate 3D-Printed Scaffolds Structurally and Functionally for Bone Tissue Engineering.

Recent interest has been focused on extracellular matrix (ECM)-based scaffolds totreat critical-sized bone injuries. In this study, urea was used to decellularize and solubilize human placenta tissue. Then, different concentrations …

Published: Jan. 9, 2025, midnight
Advances in the diagnosis and management of endometriosis: A comprehensive review.

Endometriosis is a prevalent gynecological condition characterized by the presence of endometrial-like tissue outside the uterus, leading to chronic pelvic pain and infertility. This review aims to shed light on …

Published: Jan. 9, 2025, midnight
The connection between endometriosis and secondary dysmenorrhea.

Endometriosis (EMS) is a prevalent gynecological condition characterized by the presence of endometrial tissue outside the uterus, often leading to secondary dysmenorrhea (SD), chronic pelvic pain and infertility. This review …

Published: Jan. 9, 2025, midnight
Antioxidant therapy for infertile couples: a comprehensive review of the current status and consideration of future prospects.

Oxidative stress (OS) is established as a key factor in the etiology of both male and female infertility, arising from an imbalance between reactive oxygen species (ROS) production and the …

Published: Jan. 9, 2025, midnight
Association between triglyceride-glucose index and endometriosis: results from a cross-sectional study and Mendelian randomization study.

Triglyceride-glucose (TyG) index has been found to be associated with female reproductive disorders, but its relationship with the risk of endometriosis is unknown. Therefore, the aim of this study was …

Published: Jan. 9, 2025, midnight
Optimization and Evaluation of Cannabis-Based Magistral Formulations: A Path to Personalized Therapy.

The official implementation of pharmaceutical-grade cannabis raw materials for medicinal use has permitted doctors to prescribe and pharmacists to prepare cannabis-based formulations. The objective of the pharmaceutical development and manufacturing …

Published: Jan. 9, 2025, midnight
Acute urinary retention in an adolescent female with Herlyn-Werner-Wunderlich syndrome.

Herlyn-Werner-Wunderlich syndrome (HWWS) is a rare congenital anomaly characterized by the triad of uterus didelphys, unilateral obstructed hemivagina, and ipsilateral renal agenesis. However, atypical presentations such as acute urinary retention …

Published: Jan. 9, 2025, midnight
NHS warns of 'red flags' for debilitating condition affecting one in 10 women - MSN

NHS warns of 'red flags' for debilitating condition affecting one in 10 women MSN

Published: Jan. 8, 2025, 9:33 a.m.
Validation of biomarkers and clinical scores for the detection of uterine leiomyosarcoma: a case-control study with an update of pLMS.

The diagnosis of rare uterine leiomyosarcoma (uLMS) remains a challenge given the high incidence rates of benign uterine tumors such as leiomyoma (LM). In the last decade, several clinical scores …

Published: Jan. 8, 2025, midnight
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