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A duo of redox-sensitive pore-loop cysteines controls the activity of the neural ion channel TRPM3.

Transient Receptor Potential Melastatin 3 (TRPM3) is a non-selective, Ca2+-permeable ion channel that plays a pivotal role in peripheral thermosensation and nociception. Moreover, gain-of-function variants in TRPM3 underlie a spectrum …

Published: Jan. 14, 2026, midnight
"I don't feel like me anymore": A large-scale qualitative study exploring body image disruption in endometriosis and adenomyosis.

This study explored the lived experiences of body image among individuals with a diagnosis or suspected diagnosis of endometriosis and/or adenomyosis. Using an online qualitative survey (n = 287) and …

Published: Jan. 14, 2026, midnight
Investigation of endothelin-1 receptor antagonist bosentan in a rat endometriosis model.

The study aimed to investigate the roles of endothelin-1 and endothelin receptors in a rat endometriosis model and to demonstrate how bosentan (BOS), an endothelin receptor blocker, could potentially serve …

Published: Jan. 14, 2026, midnight
Is identifying the ureter using indocyanine green in severe deep endometriosis always useful?

Fluorescence imaging using indocyanine green (ICG) has recently gained widespread use in gynecologic surgery and is considered a useful method for facilitation of ureteric identification and dissection during deep endometriosis …

Published: Jan. 14, 2026, midnight
Focal Atypical Endometrial Hyperplasia Arising Within a Deeply Infiltrating Bladder Endometriotic Nodule.

This report presents a patient with deeply infiltrating bladder endometriosis who underwent laparoscopic excision with partial cystectomy, revealing focal atypical endometrial hyperplasia within the bladder nodule on histopathology. The case …

Published: Jan. 14, 2026, midnight
In silico evaluation of procyanidin as a potential ESR1 inhibitor: docking and MD insights in uterine fibroids and endometriosis.

These are two of the most common gynecologic diseases, affecting 15% to 80% of women of childbearing age diseases. The existing treatments, such as hormonal drugs and selective estrogen receptor …

Published: Jan. 14, 2026, midnight
Advanced surgical techniques in minimally invasive surgery: multidisciplinary approach for silent obstructive uropathy in deep endometriosis.

Published: Jan. 14, 2026, midnight
Plasma extracellular vesicle modulate immune cell transcriptional responses following acute myocardial infarction.

Plasma extracellular vesicles (EVs) increase during acute myocardial infarction (MI), correlate with myocardial injury, and mobilize immune cells from the spleen to the circulation. These cells are transcriptionally activated even …

Published: Jan. 14, 2026, midnight
Genetically Causal Associations Between Adenomyosis/Endometriosis and Adverse Pregnancy Outcomes - A Two-Sample Mendelian Randomization Study.

Observational studies have indicated a potential link between adenomyosis/endometriosis and adverse pregnancy outcomes (APOs), yet the potential relationship remains uncertain.

Published: Jan. 14, 2026, midnight
Rare causes of acute abdomen in a paediatric surgery department: a 5-years review.

Acute abdomen is a common indication to surgery in paediatric emergency departments. Appendicitis is the most frequent diagnosis, followed by bowel obstruction and female genital conditions. Some rare aetiologies may …

Published: Jan. 13, 2026, midnight
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