Latest Articles

Publication Date
Progesterone and IL-6 Expression Are Modulated by Follicular Fluid in Granulosa Cell Cultures.

Endometriosis (ENDO) and poor ovarian response (POR) represent challenging conditions in assisted reproduction. Both, associated with altered follicular fluid (FF) composition, specifically impact on granulosa cell (GC) function in an …

Published: Nov. 23, 2025, midnight
[Medicinal cake-separated moxibustion inhibits ectopic endometrium remodeling by regulating TGF-β/Smad signaling in rats with endometriosis].

To investigate the mechanism of medicinal cake-separated moxibustion in inhibiting the adhesion, invasion and angiogenesis of ectopic endometriotic tissues in endometriosis (EMs) rats through transforming growth factor-β1 (TGF-β)/Sma and Mad …

Published: Nov. 21, 2025, midnight
Bidirectional Mendelian randomization and cross-sectional study reveal depression as a causal risk factor for endometriosis.

Endometriosis (EMs) and depression are both common conditions that have a significant negative impact on quality of life. However, it is still unclear about the relationship between them. The study …

Published: Nov. 21, 2025, midnight
Bioinformatic analysis and validation of candidate genes in the eutopic endometrium reveal differential expressions in diffuse adenomyosis, endometrioma, and their co-existence.

Adenomyosis and endometriosis are hormone-dependent benign gynecological disorders with overlapping features suggesting that they may share a common origin despite being considered distinct entities. This study compares the expression of …

Published: Nov. 21, 2025, midnight
MiRNome alterations drive the malignant transformation of endometriosis into endometriosis-correlated ovarian cancer.

Endometriosis (EMS) is a chronic gynecological condition affecting 6-10% of reproductive-age women. These lesions, albeit of benign nature, present cancer-like features, and may progress to epithelial ovarian cancer (EOC) through …

Published: Nov. 21, 2025, midnight
THBS1 identificated as an endometriosis biomarker through evidence from single-cell and bulk transcriptomic profiling.

Endometriosis affects a substantial number of women of reproductive age, yet current diagnostic methods rely on invasive procedures. To address this limitation, we investigated THBS1 as a potential biomarker and …

Published: Nov. 21, 2025, midnight
Establishment and Characterization of a New Immortalized Human Adenomyosis Epithelial-Like Cell Line, tAEC21†.

Adenomyosis occurs when endometrial glands and stroma grow within the uterine myometrium. As a clinically significant disease, adenomyosis causes substantial pelvic pain and heavy menstrual bleeding. It remains understudied due …

Published: Nov. 20, 2025, midnight
Endometriosis - on the intersection of modern environmental pollutants and ancient genetic regulatory variants.

Endometriosis is a chronic, estrogen-driven inflammatory disorder affecting approximately 10% of reproductive-aged women globally. Despite increasing genomic insights into advanced-stage disease, the genetic underpinnings of early-stage endometriosis remain poorly understood, …

Published: Nov. 20, 2025, midnight
Therapeutic targeting of interleukin-17C signaling in carcinogenesis of endometriosis.

Endometriosis-associated ovarian carcinoma (EAOC) predominantly arises from the malignant transformation of endometriomas, yet the mechanism is incompletely defined. Spatial transcriptomic analysis of human specimens of normal endometrium, endometriomas, and EAOC …

Published: Nov. 20, 2025, midnight
Extracellular Trap-Related Genes as Potential Diagnostic Biomarkers for Endometriosis.

Endometriosis (EM), a prevalent gynecological disorder in reproductive-age women, lacks reliable noninvasive diagnostic tools. EM may be detected by neutrophil extracellular traps (NETs), which are essential to inflammation and immunological …

Published: Nov. 19, 2025, midnight
Link copied to clipboard!
Subscribe to Our Newsletter

Stay updated with our latest articles!