Endometriosis appears to have a multilayered etiology, with genetic and epigenetic factors each contributing half of the pathogenesis. The molecular processes that underlie the onset of endometriosis are yet unclear, …
As a complex chronic gynecological disorder characterized by multifaceted etiology involving genetics, environment, immunity and inflammation, endometriosis (EM) has long been a significant concern for women of reproductive age worldwide. …
The interaction between vitamin D and the immune system is perhaps the most well recognised extraskeletal facet of vitamin D, encompassing early studies of therapy for TB and leprosy through …
This study advances sustainable pharmaceutical research for endometriosis by developing in vitro 3D cell culture models of endometriotic pathophysiology that allow antifibrotic drug candidates to be tested. Fibrosis is a …
Endometriosis is the presence of hormonally sensitive endometrium-like tissue outside the uterus. It is a common condition, affecting 10% of reproductive-age people assigned as female at birth. Although usually occurring …
The impact of endometriosis and adenomyosis on reproduction and pregnancy is significant, with both conditions linked to increased rates of infertility, poor ovarian function in women with endometriosis, and elevated …
Endometriosis affects approximately 10% of premenopausal women, with urinary tract involvement in 1% of cases. Ureteric endometriosis is a rare, typically asymptomatic, cause of obstructive renal failure. We present the …
There is a growing need to develop new MRI sequences to identify and characterize hemorrhagic foci within endometriosis lesions. These foci are pivotal, as they represent a significant component of …
We recognized a paucity of accessible, evidence-based, empowering patient-centred resources for those with endometriosis-associated dyspareunia. Affecting more than 50% of people with endometriosis, dyspareunia can significantly impact relationships, chronic pain …
To evaluate the association between contemporary hormonal contraceptive use and the risk of incident ischaemic stroke and myocardial infarction.