M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy With Comorbid Traits.
Endometriosis is a common gynecologic condition that causes chronic, life-altering symptoms including pain and infertility. There is an urgent need for new non-hormonal targeted therapeutics to treat endometriosis, but until …
Helixor A enhances natural killer cell activity by induction of PAI-1 expression through the p38/MAPK signaling pathway.
Helixor A, an anticancer drug, has an immunostimulatory effect that increases T and natural killer (NK) cell activity in patients with cancer and endometriosis. However, the molecular mechanisms underlying its …
Sigmoid colon endometriosis as an uncommon cause of large bowel obstruction: A case report.
Large bowel obstruction (LBO) is most commonly caused by neoplasms, but rare etiologies like endometriosis should be considered, as bowel involvement can mimic other gastrointestinal disorders and lead to obstruction. …