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Therapeutic Effects and Mechanisms of Alcohol Extracts from Polygala fallax Hemsl on Endometriosis in Rats.

Endometriosis is a chronic estrogen-dependent inflammatory disease that significantly affects women's health. Polygala fallax Hemsl. (PFH), a traditional Zhuang medicine, has been frequently used for gynecological disorders. This study investigated …

Published: March 14, 2025, midnight
Re-Evaluating the Use of Glyphosate-based Herbicides: Implications on Fertility.

Glyphosate-based herbicides (GBHs) are the most widely used herbicides in the United States, accounting for 19% of estimated global use. Although the Environmental Protection Agency (EPA) has reaffirmed that the …

Published: March 12, 2025, midnight
Adnexal Incarceration in a Posterior Pelvic Peritoneal Defect Associated with Ovarian Torsion: A Case Report.

Ovarian torsion is one of the gynecological emergencies and surgical intervention is the standard management for ovarian salvage as well as reveals some unexpected anatomical defects that increase the risk …

Published: March 11, 2025, midnight
Abdominal Wall Reconstruction in Abdominal Wall Endometriosis: A Case Report and Literature Review.

Abdominal wall endometriosis (AWE) is a rare condition representing 1% of patients operated for endometriosis. We describe a case of a 26-year-old woman, with a history of cesarean delivery, who …

Published: March 11, 2025, midnight
The Molecular and Cellular Mechanisms of Endometriosis: From Basic Pathophysiology to Clinical Implications.

Endometriosis is a complex gynecological disorder characterized by endometrial-like tissue growing outside the uterus, leading to chronic pain, infertility, and reduced quality of life. Its pathophysiology involves genetic, epigenetic, immune, …

Published: March 10, 2025, midnight
Evaluation of Long-COVID Syndrome in a Cohort of Patients with Endometriosis or Adenomyosis.

Background: Long-COVID is characterized by the persistency of COVID-19 symptoms beyond 12 weeks, and it is probably consequent to immune dysregulation induced by SARS-CoV-2 infection. Immune dysregulation is associated with …

Published: March 8, 2025, midnight
Psychological Distress and Quality of Life in Women With Endometriosis: A Narrative Review of Therapeutic Approaches and Challenges.

The chronic gynecological disorder endometriosis is a debilitating condition for women's physical and psychological health. Endometriosis is a disease that causes endometrial-like tissue to grow outside the uterus and causes …

Published: March 6, 2025, midnight
Altered Mitochondrial Morphology and Reduced Cardiolipin Levels in Oocytes of Endometriosis Model Mice: Implications for Mitochondrial Dysfunction in Infertility.

BACKGROUND Women with endometriosis experience significantly reduced fertility, potentially linked to mitochondrial dysfunction. This study investigates the impact of endometriosis on oocyte mitochondrial morphology and cardiolipin levels, key indicators of …

Published: March 5, 2025, midnight
Does interdisciplinary group care for the treatment of endometriosis improve pain interference: protocol for a pilot randomised controlled trial at an urban academic medical centre.

Endometriosis affects 10-15% of people assigned female at birth and can cause chronic pelvic pain and impair many domains of quality of life, such as fertility, mood and bladder, bowel …

Published: March 5, 2025, midnight
Polygenic Scores for Dizygotic Twinning: Insights into the Genetic Architecture of Female Fertility.

Natural dizygotic twinning (DZT) results from hyper-ovulation and is considered an indicator of female fertility. DZT has low polygenicity, with only 0.20% of SNPs estimated to have a nonzero effect. …

Published: March 5, 2025, midnight
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