Single-cell profiling and machine learning identify cuproptosis-related fibroblast subpopulations and fibrogenesis modulator AEBP1 in endometriosis.
Endometriosis is characterized by progressive fibrosis and limited therapeutic options. Cuproptosis, a copper-dependent form of regulated cell death, has been implicated in multiple pathological conditions, but its relevance to fibroblast-mediated …
HSD11B1 suppresses ferroptosis in endometrial stromal cells through the JUND/IL-10 axis to promote endometriosis progression.
Endometriosis (EMs) is a common gynecological disorder characterized by ectopic endometrial tissue growth, leading to chronic inflammation and pelvic pain. Despite its high prevalence, the molecular mechanisms underlying EMs remain …
A nomogram integrating a novel uterine isthmus ratio (APTUIR), sonographic signs and clinical symptoms for predicting posterior deep endometriosis.
This study aims to propose a novel, reproducible transvaginal ultrasound (TVUS) measurement-anterior-posterior wall thickness of the uterine isthmus ratio (APTUIR)-and to construct a nomogram model integrating this parameter with other …