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Identification of metabolic reprogramming-associated biomarkers in endometriosis through integrated bioinformatics analysis.

Endometriosis (EMs), a common gynecological disorder, involves complex molecular mechanisms. Metabolic reprogramming (MR) has been recognized as a hallmark of EMs, contributing to lesion survival and immune microenvironment remodeling. This …

Published: Oct. 30, 2025, midnight
Integrative microbiome-metabolomics identifies Pseudomonas as a potential pathogenic factor in endometriosis.

Endometriosis (EMS) is a chronic disease characterized by unclear etiology, influenced by various genetic and environmental factors, with no definitive biomarkers available for early screening. Recent studies suggest that the …

Published: Oct. 30, 2025, midnight
Gene Expression Profiling and Pathway Analysis of the Effect of Dienogest on Ovarian Endometriosis: A Comparative Study.

Endometriosis affects about 10% of reproductive-age women and can be managed through medical treatments, surgical intervention, or both. Approximately 40%-50% of patients experience recurrence within 5 years after surgery. Therefore, …

Published: Oct. 29, 2025, midnight
Multi-institutional study of mesonephric-like adenocarcinoma: its clinicopathological characteristics and histogenetic association with ectopic endometrium.

To explore the clinicopathological features and origin of mesonephric-like adenocarcinomas (MLAs), 83 cases diagnosed or suspected to be MLAs were collected from various institutions in Japan. We clearly classified 78 …

Published: Oct. 29, 2025, midnight
The effects of antioxidant supplementation on pain, oxidative stress markers, and clinical pregnancy rate in women with endometriosis: a systematic review and meta-analysis of randomized controlled trials.

Endometriosis is a chronic inflammatory disease characterized by pelvic pain and infertility, with oxidative stress playing a key role in its pathogenesis. Although antioxidant supplementation has been proposed as a …

Published: Oct. 29, 2025, midnight
Impact of the Lipid–Inflammation Axis on Endometriosis Risk: A Multicenter Case–Control Study Using Mediation Analysis - Frontiers

Impact of the Lipid–Inflammation Axis on Endometriosis Risk: A Multicenter Case–Control Study Using Mediation Analysis Frontiers

Published: Oct. 28, 2025, 9:44 p.m.
Global, regional, and national burden and trends of endometriosis, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2050 - BMC Women's Health

Global, regional, and national burden and trends of endometriosis, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 2050 BMC Women's Health

Published: Oct. 28, 2025, 1:02 p.m.
Enhanced analysis of endometriosis patients’ plasma using #Enzian annotation highlights potential biomarkers for early-stages of disease - Nature

Enhanced analysis of endometriosis patients’ plasma using #Enzian annotation highlights potential biomarkers for early-stages of disease Nature

Published: Oct. 28, 2025, 9:29 a.m.
Serum response factor is essential for endometrial function and prevention of inflammatory fibrosis.

Pregnancy requires a supportive uterine environment facilitated by steroid hormone-regulated differentiation of endometrial stromal fibroblasts into decidual cells and tight control of inflammation. Serum response factor (SRF) is a widely …

Published: Oct. 28, 2025, midnight
Global, regional, and national burden and trends of endometriosis, 1990-2021: an analysis of the global burden of disease study 2021 and forecast to 2050.

Endometriosis is highly prevalent but remains under-researched. This study, using the latest data, aims to provide a comprehensive assessment of the burden of endometriosis on a global scale.

Published: Oct. 28, 2025, midnight
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