Reduced GEN1 Expression Is Associated with Elevated DNA Damage and Impaired Proliferation in Endometriosis-Derived Endometrial Organoids.
Endometriosis affects approximately 10% of reproductive-age women and is associated with genomic instability; however, the contribution of specific DNA repair deficiencies remains poorly understood. This study investigated the expression and …
The role of psychological care in the treatment of gynecological disorders in girls and young women - an interdisciplinary perspective.
This review article explores the psychological dimension of gynecological disorders in girls and young women, emphasizing the need for interdisciplinary approaches in medical care. Gynecological conditions such as endometriosis, polycystic …
Catheter-Directed Sclerotherapy Versus Ovarian Cystectomy for Unilateral Ovarian Endometrioma: A Pilot Randomized Controlled Trial.
Background: Ovarian cystectomy is standard treatment for endometrioma but is associated with decreased ovarian reserve. Catheter-directed sclerotherapy (CDS) is an ovary-sparing image-guided alternative; however, supporting evidence comprises retrospective comparative and …
Endo-SOFT: study protocol for a national multicentre randomised controlled trial - first-line surgery versus first-line assisted reproductive technologies in patients with advanced endometriosis.
Endometriosis is a chronic, inflammatory and oestrogen-dependent disease frequently causing infertility. Assisted reproductive technologies (ART) are often required to achieve pregnancy, especially in women with advanced endometriosis. To date, there …